Zobrazeno 1 - 10
of 683
pro vyhledávání: '"L Maas"'
Autor:
Jennifer Kosinski, Antonio Sechi, Johanna Hain, Sophia Villwock, Stefanie Anh Ha, Maximilian Hauschulz, Michael Rose, Florian Steib, Nadina Ortiz‐Brüchle, Lara Heij, Sanne L. Maas, Emiel P. C. van derVorst, Thomas Knoesel, Annelore Altendorf‐Hofmann, Ronald Simon, Guido Sauter, Jan Bednarsch, Danny Jonigk, Edgar Dahl
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1486-1509 (2024)
Inter‐alpha‐trypsin inhibitor heavy chain 5 (ITIH5) has been identified as a metastasis suppressor gene in pancreatic cancer. Here, we analyzed ITIH5 promoter methylation and protein expression in The Cancer Genome Atlas (TCGA) dataset and three
Externí odkaz:
https://doaj.org/article/75b2e5c402634669a62206e5036d9a5a
Autor:
Svenja Adam, Sanne L. Maas, Rosanna Huchzermeier, Leonida Rakateli, Kathrin Abschlag, Mathias Hohl, Liangliang Liao, Matthias Bartneck, Margee Teunissen, Kristiaan Wouters, Donato Santovito, Joachim Jankowski, Erik A.L. Biessen, Emiel P.C. van der Vorst
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105293- (2024)
Summary: Background: Female mice are more resistant to obesogenic effects of a high-fat diet (HFD), compared to male mice. Although the underlying mechanisms are poorly understood, sex hormones seem to play an important role. Interestingly, the activ
Externí odkaz:
https://doaj.org/article/5c34e5143fad4d869b8e96f2511c8b5a
Autor:
Zachary L. Maas, Robin D. Dowell
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract In experiments with significant perturbations to transcription, nascent RNA sequencing protocols are dependent on external spike-ins for reliable normalization. Unlike in RNA-seq, these spike-ins are not standardized and, in many cases, depe
Externí odkaz:
https://doaj.org/article/e33bb6c2e04c4f18b3815360846f29eb
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6213 (2024)
Circulating low-density lipoprotein (LDL) levels are a major risk factor for cardiovascular diseases (CVD), and even though current treatment strategies focusing on lowering lipid levels are effective, CVD remains the primary cause of death worldwide
Externí odkaz:
https://doaj.org/article/af4a89c215c34cf88d0307834d1190bd
Autor:
Hanna Malyaran, Rogerio B. Craveiro, Sinan Mert, Christian Niederau, Sanne L. Maas, Emiel P. C. van der Vorst, Frank Hölzle, Wilhelm Jahnen-Dechent, Michael Wolf, Sabine Neuss
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3207 (2024)
Periodontal defects’ localization affects wound healing and bone remodeling, with faster healing in the upper jaw compared to the lower jaw. While differences in blood supply, innervation, and odontogenesis contribute, cell-intrinsic variances may
Externí odkaz:
https://doaj.org/article/d20e7a17f55449e0999a27aa5e7acb73
Autor:
Melisa S DeGroot, Byron Williams, Timothy Y Chang, Maria L Maas Gamboa, Isabel M Larus, Garam Hong, J Christopher Fromme, Jun Liu
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002272 (2023)
Secreted modular calcium-binding proteins (SMOCs) are conserved matricellular proteins found in organisms from Caenorhabditis elegans to humans. SMOC homologs characteristically contain 1 or 2 extracellular calcium-binding (EC) domain(s) and 1 or 2 t
Externí odkaz:
https://doaj.org/article/fb0b94a8d652448aa6fe25047e4b530e
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Objective To evaluate the effectiveness of personalized and home-based speech therapy on quality of life, intelligibility, and social participation for people with Parkinson’s disease (PD) who have a reduced intelligibility of speech. Back
Externí odkaz:
https://doaj.org/article/4e9a528e5a474f22b18e9c060431573b
Autor:
L. Maas, J. Kellenaers, G. van Mastrigt, S.M.J van Kuijk, M.C.G. Vlooswijk, M. Hiligsmann, S. Klinkenberg, L. Wagner, J. Nelissen, O.E.M.G. Schijns, H.J.M. Majoie, K. Rijkers
Publikováno v:
Epilepsy & Behavior Reports, Vol 24, Iss , Pp 100635- (2023)
Although effectiveness of Resective Epilepsy Surgery (RES) for patients with drug-resistant epilepsy (DRE) is widely proven, research on the impact of societal costs (SC) is lacking. The aim of this study is to provide both clinical and economic outc
Externí odkaz:
https://doaj.org/article/bb60bfe21cb8461ebac6f23597f910fb
Autor:
Emiel P. C. van der Vorst, Sanne L. Maas, Kosta Theodorou, Linsey J. F. Peters, Han Jin, Timo Rademakers, Marion J. Gijbels, Mat Rousch, Yvonne Jansen, Christian Weber, Michael Lehrke, Corinna Lebherz, Daniela Yildiz, Andreas Ludwig, Jacob F. Bentzon, Erik A. L. Biessen, Marjo M. P. C. Donners
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionThe transmembrane protease A Disintegrin And Metalloproteinase 10 (ADAM10) displays a “pattern regulatory function,” by cleaving a range of membrane-bound proteins. In endothelium, it regulates barrier function, leukocyte recruitment
Externí odkaz:
https://doaj.org/article/f70375b98dbc4f308c54dc71482a5393
Autor:
Bibian M.E. Tullemans, Mieke F.A. Karel, Valentine Léopold, Marieke S. ten Brink, Constance C.F.M.J. Baaten, Sanne L. Maas, Alex F. deVos, Johannes A. Eble, Marten R. Nijziel, Emiel P.C. van derVorst, Judith M.E.M. Cosemans, Johan W.M. Heemskerk, Theodora A.M. Claushuis, Marijke J.E. Kuijpers
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 685-699 (2021)
Abstract All irreversible Bruton tyrosine kinase (Btk) inhibitors including ibrutinib and acalabrutinib induce platelet dysfunction and increased bleeding risk. New reversible Btk inhibitors were developed, like MK‐1026. The mechanism underlying in
Externí odkaz:
https://doaj.org/article/44007a92296c4e6e8eb464bf7bca834a