Zobrazeno 1 - 7
of 7
pro vyhledávání: '"L M Spain"'
Publikováno v:
International Immunology. 10:923-933
Mutagenic analyses have identified structural motifs important for TCR-mediated signaling in the antigen-binding chains, CD3 and zeta subunits of the TCR complex. In this study, we altered selected residues in the transmembrane and extracellular cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15d725bb2d583c5bb614cccaaa5bd1a
https://doi.org/10.1093/intimm/10.7.923
https://doi.org/10.1093/intimm/10.7.923
Publikováno v:
The Journal of Immunology. 156:2294-2299
A single dose of CTLA4Ig, an inhibitor of CD28-mediated T cell costimulation, given 2 days after transplantation induces specific unresponsiveness to alloantigens in vivo. However, the mechanisms responsible are unknown. Using pigeon cytochrome c as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f88c66154b36095deb36e3a09a8a9c
https://doi.org/10.4049/jimmunol.156.6.2294
https://doi.org/10.4049/jimmunol.156.6.2294
Publikováno v:
The Journal of Immunology. 152:1709-1717
The developmental fate of an immature T cell is determined in the thymus. Depending on the specificity of its TCR, a thymocyte receives signals to either die or differentiate. We have used fetal thymic organ cultures derived from TCR transgenic mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c7f81b350530141c89c07cb7d0706a
https://doi.org/10.4049/jimmunol.152.4.1709
https://doi.org/10.4049/jimmunol.152.4.1709
Publikováno v:
Blood. 95(3)
The ets-family transcription factor PU.1 is required for the proper development of both myeloid and lymphoid progenitors. We used PU. 1-deficient animals to examine the role of PU.1 during dendritic cell development. PU.1(-/-)animals produce lymphoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79d1371a7f7f26332f7fc40ca73ccbe5
https://pubmed.ncbi.nlm.nih.gov/10648399
https://pubmed.ncbi.nlm.nih.gov/10648399
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(5)
These studies address the role of PU.1 in T cell development through the analysis of PU.1-/- mice. We show that the majority of PU.1-/- thymocytes are blocked in differentiation prior to T cell commitment, and contain a population of thymocyte progen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a62df9eab628031ec138d19876a4506
https://pubmed.ncbi.nlm.nih.gov/10453009
https://pubmed.ncbi.nlm.nih.gov/10453009
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(6)
A single dose of CTLA4Ig, an inhibitor of CD28-mediated T cell costimulation, given 2 days after transplantation induces specific unresponsiveness to alloantigens in vivo. However, the mechanisms responsible are unknown. Using pigeon cytochrome c as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9637cb2ccf59cb6b45329bc9aa1dbea7
https://pubmed.ncbi.nlm.nih.gov/8690920
https://pubmed.ncbi.nlm.nih.gov/8690920
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(4)
The developmental fate of an immature T cell is determined in the thymus. Depending on the specificity of its TCR, a thymocyte receives signals to either die or differentiate. We have used fetal thymic organ cultures derived from TCR transgenic mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a00c2d55320068e74273dfc9cb510b8a
https://pubmed.ncbi.nlm.nih.gov/8120380
https://pubmed.ncbi.nlm.nih.gov/8120380