Zobrazeno 1 - 10 of 25 pro vyhledávání: '"L M Sayre"'
3
Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein
Autor: E A, Podrez, G, Hoppe, J, O'Neil, L M, Sayre, N, Sheibani, H F, Hoff
Publikováno v: Journal of lipid research. 41(9)
Oxidation of low density lipoproteins (LDL) induced by incubation with Cu(2+) ions results in the formation of a heterogeneous group of aldehydic adducts on lysyl residues (Lys) of apolipoprotein B (apoB) that are thought to be responsible for the up
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a9a5cf71b1e53ce79b718c8d42f91ea
https://pubmed.ncbi.nlm.nih.gov/10974053
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4
Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane
Autor: J, Chun, U M, Kent, R M, Moss, L M, Sayre, P F, Hollenberg
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 28(8)
2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine, was tested for its ability to inactivate cytochrome P450s (P450s) 2B1 and 2B6. PPP inactivated the 7-(benzyloxy)resorufin O-dealkylation activity of liver microsomes obtained from p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::699890cba2589b5baaac5320b1f77edd
https://pubmed.ncbi.nlm.nih.gov/10901699
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6
Identification and expression of the Na+/H+ exchanger in mammalian cerebrovascular and choroidal tissues: characterization by amiloride-sensitive [3H]MIA binding and RT-PCR analysis
Autor: R N, Kalaria, D R, Premkumar, C W, Lin, S N, Kroon, J Y, Bae, L M, Sayre, J C, LaManna
Publikováno v: Brain research. Molecular brain research. 58(1-2)
We report the initial characterization of [3H]5-(N-methyl-N-isobutyl)amiloride (MIA) binding to the Na+/H+ exchanger (NHE) and expression of its gene in mammalian cerebrovascular, choroidal and neocortical tissues. [3H]MIA bound reversibly to particu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ef60edbaae23fec2422147826a4fe21
https://pubmed.ncbi.nlm.nih.gov/9685633
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7
Advanced lipid peroxidation end-products in Alexander's disease
Autor: R J, Castellani, G, Perry, P L, Harris, M L, Cohen, L M, Sayre, R G, Salomon, M A, Smith
Publikováno v: Brain research. 787(1)
Rosenthal fibers (RF), intra-astrocytic hyaline inclusions, accumulate in various pathological conditions and are the histological hallmark of Alexander's disease. While the major protein components of RF have been identified, the factors accounting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d02c893afa92f15394116b3f9185cedb
https://pubmed.ncbi.nlm.nih.gov/9518535
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8
Effect of methimazole, an FMO substrate and competitive inhibitor, on the neurotoxicity of 3,3'-iminodipropionitrile in male rats
Autor: Mary Beth Genter, C. G. Nace, L. M. Sayre, Kevin M. Crofton
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 37(2)
This study was designed to examine the role of flavin-containing monooxygenase (FMO) on the auditory and vestibular neurotoxicity of 3,3'-iminodipropionitrile (IDPN) using the FMO substrate and competitive inhibitor methimazole (MMI). Specifically, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bd31b13fa1f5624600544b55251546
https://pubmed.ncbi.nlm.nih.gov/9242586
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