Zobrazeno 1 - 10
of 34
pro vyhledávání: '"L M Korkodinova"'
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 3, Pp 197-200 (2010)
There was investigated the possibility of using the service Web 2.0 while carrying out a distance course on pharmaceutical chemistry. The methodology of holding Internet seminar was described, the results were analysed.
Externí odkaz:
https://doaj.org/article/e2cf1ca8db89445db1db72438dab0fb5
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 4, Pp 165-167 (2010)
The physical and chemical properties were studied; the metodics of proof the identity, good quality and quantitative analysis of substance of amide N-allylanthranylic acid are developed. This substance was recommended for predclinical investigation a
Externí odkaz:
https://doaj.org/article/c9e9a5dafa714aac8e9bfc00cda5d3a2
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 4, Pp 295-297 (2010)
The amide of N-allylanthranylic acid was synthesized; the structure was confirmed by IR-, IMR- and chromate-mass spectra, the anti-inflammatory, analgesic, antipyretic, ulcer, antihypoxic activities and acute toxicity were studied.
Externí odkaz:
https://doaj.org/article/c7fe80e920ec4e91a58a6d0dc2a37e5a
Publikováno v:
Pharmaceutical Chemistry Journal. 56:1060-1063
Autor:
K. V. Andryukov, L. M. Korkodinova
Publikováno v:
Pharmaceutical Chemistry Journal. 56:889-893
Autor:
A. A. Kurbatova, R. R. Makhmudov, L. M. Korkodinova, A. F. Gazizova, E. R. Kurbatov, A. A. Bobyleva
Publikováno v:
Pharmaceutical Chemistry Journal. 52:965-968
A series of R-benzylidenehydrazides of NH-furoyl-5-iodoanthranilic acid were synthesized by condensing NH-furoyl-5-iodoanthranilic acid hydrazide with aromatic aldehydes. Their structures were confirmed using IR and PMR spectroscopy. Their analgesic
Autor:
L. M. Korkodinova, K. V. Andryukov
Publikováno v:
Medicina. 7:94-109
Autor:
K. V. Andryukov, L. M. Korkodinova
Publikováno v:
Pharmaceutical Chemistry Journal. 52:411-414
Molecular docking of 22 N-aroyl-substituted halo(H)anthranilic acid amides and hydrazides with cyclooxygenase 1 (COX1) is described. The dependence of anti-inflammatory activity (AIA) on scoring functions (BeCOX1, ImeCOX1, KiCOX1) and lipophilicity c
Autor:
L. M. Korkodinova, K. V. Andryukov
Publikováno v:
Pharmaceutical Chemistry Journal. 50:159-164
Ionization constants (pKa and pKb) of N-substituted mono(di)halo(H)anthranilic acids and their amides and hydrazides were studied as functions of their quantum-chemical parameters. The predicted pKa and pKb values calculated for 10 new compounds of t
Autor:
L. G. Mardanova, E. R. Kurbatov, A. G. Gol’dshtein, L. M. Korkodinova, T. I. Yarygina, A. S. Botalova
Publikováno v:
Pharmaceutical Chemistry Journal. 48:791-794
N-Substituted 5-iodo(H)anthranilic acid amides were synthesized by acylation of 5-iodoanthranilic acid amide in benzene with heating and by alkylation of anthranilic acid amide at room temperature. The synthesized compounds were studied for analgesic