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Methods for the study of sequence-specific binding of proteins to the HCV RNA genome

Autor: L M, Kaplan, R T, Chung

Publikováno v: Methods in molecular medicine. 19

The appropriate formation of specific RNA-protein complexes regulates the normal synthesis, trafficking, and metabolism of intracellular RNA. For RNA viruses, these interactions are essential for replication and translation of the viral genome, as we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48e359ee4fe61d5c4eda1c835694e258
https://pubmed.ncbi.nlm.nih.gov/21374380

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Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus

Autor: R T, Chung, A, Monto, J L, Dienstag, L M, Kaplan

Publikováno v: Journal of medical virology. 58(4)

A striking association has been demonstrated recently between mutations in amino acid residues 2209-2248 of the nonstructural protein 5a (NS5a) region of hepatitis C virus (HCV) and sustained responses to interferon in Japanese patients infected with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba8e2cc13e7fb0598cabb6cd7144b7fa
https://pubmed.ncbi.nlm.nih.gov/10421401

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Analysis of impaired exercise capacity in patients with cirrhosis

Autor: S K, Epstein, R L, Ciubotaru, M D, Zilberberg, L M, Kaplan, C, Jacoby, R, Freeman, M M, Kaplan

Publikováno v: Digestive diseases and sciences. 43(8)

Exercise limitation in cirrhosis is typically attributed to a cirrhotic myopathy (without impaired oxygen utilization) and/or a cardiac chronotropic dysfunction. We performed symptom-limited cardiopulmonary exercise testing in 19 cirrhotics without c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::314130e7bff99b6bbcfb4b8345469be2
https://pubmed.ncbi.nlm.nih.gov/9724156

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Respiratory dysfunction in amyotrophic lateral sclerosis

Autor: L M, Kaplan, D, Hollander

Publikováno v: Clinics in chest medicine. 15(4)

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of the voluntary motor system. Involvement of the respiratory system is inevitable and leads to the development of respiratory failure, the usual cause of death in this d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bfad230e23f4d41813d55a6a09af377d
https://pubmed.ncbi.nlm.nih.gov/7867282

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Parenterally transmitted hepatitis: viruses, vaccines, and antiviral therapy

Autor: R T, Chung, L M, Kaplan

Publikováno v: Comprehensive therapy. 19(4)

The introduction of safe and effective vaccines as well as the identification of antiviral therapy that eradicates virus in many infected patients augurs well for the control of HBV and, by extension, HDV infection. The key to ultimate success will b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55269d2e2310c2e165ac7c06baa6d74b
https://pubmed.ncbi.nlm.nih.gov/7505215

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On the interations of galanin within the hypothalamic-pituitary axis of the rat

Autor: Shing Chuan Hooi, S. M. Gabriel, D. M. Maiter, J. I. Koenig, R. M. Strauss, J. B. Martin, L. M. Kaplan

Publikováno v: Galanin ISBN: 9781349126668

The hypothalamus has been shown to be densely populated by galanin-containing neuron cell bodies. The greatest concentration of cells reside in the arcuate nucleus. In addition, galanin immunopositive cells are present in the paraventricular (PVN), s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b79f511377dbfcf0de00a2a3c7e07623
https://doi.org/10.1007/978-1-349-12664-4_25

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Specific alpha 1-adrenergic receptor subtypes modulate catecholamine-induced increases and decreases in ventricular automaticity

Autor: Gabriella Malfatto, Susan F. Steinberg, U del Balzo, Michael R. Rosen, L M Kaplan

Publikováno v: Circulation research. 67(6)

Fifty percent of adult canine Purkinje fibers manifest a decrease in automaticity in response to alpha 1-adrenergic stimulation with 10(-10)-10(-8) M norepinephrine (NE), and 50% manifest an increase. In contrast, most neonatal Purkinje fibers show a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315e6396102d13fc12bf5787efdfe4e9
https://pubmed.ncbi.nlm.nih.gov/2173982

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Adenovirus DNA Replication in Soluble Extracts of Infected Cell Nuclei

Autor: J. Maritato, M. Abboud, M. S. Horwitz, L. M. Kaplan, Louise T. Chow, Thomas R. Broker

Publikováno v: Cold Spring Harbor Symposia on Quantitative Biology. 43:769-780

Synthesis of viral DNA after infection of prokaryotic and eukaryotic cells has been studied to understand the replication of the viral genome itself, as well as to serve as a substrate for the analysis of components necessary for host-chromosomal rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94947dc7ca2151ae4303fd289446ec92
https://doi.org/10.1101/sqb.1979.043.01.084

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Replication of adenovirus type 2 DNA in vitro

Autor: M S Horwitz, L M Kaplan, R E Kelinman

Publikováno v: Proceedings of the National Academy of Sciences. 74:4425-4429

A soluble replication system that synthesizes full-sized adenovirus DNA molecules has been developed. The extraction of infected HeLa nuclei solubilizes approximately 25% of the viral replicating DNA and leaves the HeLa chromatin associated with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b337c08920fb49cf12bcff90e433716e
https://doi.org/10.1073/pnas.74.10.4425

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