Zobrazeno 1 - 10
of 47
pro vyhledávání: '"L M Havekes"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2465-2472 (1997)
An in vitro assay to study lipolysis of very low density lipoproteins (VLDL) by heparan sulfate proteoglycan (HSPG-bound lipoprotein lipase (LPL) was developed. Optimal conditions for VLDL lipolysis by HSPG-bound LPL were obtained by incubating plast
Externí odkaz:
https://doaj.org/article/d2714048196846bba29c32e1548d5620
Autor:
P Lombardi, E J Sijbrands, K van de Giessen, A H Smelt, J J Kastelein, R R Frants, L M Havekes
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 4, Pp 860-867 (1995)
Familial hypercholesterolemia (FH) results from mutations in the low density lipoprotein receptor (LDLR) gene. We applied denaturing gradient gel electrophoresis (DGGE) to screen for sequence variations in the coding and splice site consensus sequenc
Externí odkaz:
https://doaj.org/article/1db1e2cb6d474bea9a1b9a9b0516e091
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 12, Pp 1621-1627 (1988)
Recently, we determined the apolipoprotein E (apoE) phenotype distribution in 2,000 randomly selected 35-year-old male individuals by slab gel isoelectric focusing of delipidated plasma samples, followed by immunoblotting using anti-apoE antiserum. T
Externí odkaz:
https://doaj.org/article/a8db4cde2e664fb1a21ae81c0d771e89
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 4, Pp 455-463 (1987)
A new method for the apolipoprotein E phenotyping has been developed. The method is based on isoelectric focusing of either delipidated or guanidine-HC1-treated serum or plasma in a horizontal slab gel system followed by immunoblotting using either p
Externí odkaz:
https://doaj.org/article/734c90b94cfe421b90421df8518364c1
Publikováno v:
Twin Research (2000). 3:152-158
The effects of apolipoprotein (a), apolipoprotein-E, and apolipoprotein-A4 isoforms on quantitative lipoprotein(a) [Lp(a)] levels were assessed in a sample of 142 Dutch families consisting of two parents and their adolescent twin offspring. A total h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5e6e0854c393d37faf103b6e1c04a4
https://doi.org/10.1375/136905200320565436
https://doi.org/10.1375/136905200320565436
Autor:
C P, Coomans, J J, Geerling, S A A, van den Berg, H C, van Diepen, N, Garcia-Tardón, A, Thomas, J P, Schröder-van der Elst, D M, Ouwens, H, Pijl, P C N, Rensen, L M, Havekes, B, Guigas, J A, Romijn
Publikováno v:
British journal of pharmacology. 170(4)
Topiramate improves insulin sensitivity, in addition to its antiepileptic action. However, the underlying mechanism is unknown. Therefore, the present study was aimed at investigating the mechanism of the insulin-sensitizing effect of topiramate both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b40fdf12de916de0a9504b3b90084c8
https://pubmed.ncbi.nlm.nih.gov/23957854
https://pubmed.ncbi.nlm.nih.gov/23957854
Autor:
G Schmitz, Marja-Riitta Taskinen, L M Havekes, S Humphries, A K Soutar, Lawrence P. Aggerbeck, R Zechner
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 11:1120-1127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7bea422394791a7cdeac10ee82ae773
https://doi.org/10.1161/01.atv.11.4.1120
https://doi.org/10.1161/01.atv.11.4.1120
Publikováno v:
Journal of neuroendocrinology. 20(1)
Obese humans are often insulin- and leptin resistant. Since leptin can affect glucose metabolism, it is conceivable that a lack of leptin signal transduction contributes to insulin resistance. It remains unclear whether leptin affects glucose metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59a41847ed59b18b867acddf51ff8897
https://pubmed.ncbi.nlm.nih.gov/18081560
https://pubmed.ncbi.nlm.nih.gov/18081560
Autor:
E, Fliers, F, Kreier, P J, Voshol, L M, Havekes, H P, Sauerwein, A, Kalsbeek, R M, Buijs, J A, Romijn
Publikováno v:
Journal of neuroendocrinology. 15(11)
Neuroendocrine research has altered the traditional perspective of white adipose tissue (WAT) as a passive store of triglycerides. In addition to fatty acids, WAT produces many hormones and can therefore be designated as a traditional endocrine gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63495ce58dccbe9b11efcd7b78d5b3b1
https://pubmed.ncbi.nlm.nih.gov/14622429
https://pubmed.ncbi.nlm.nih.gov/14622429
Publikováno v:
Journal of lipid research. 42(10)
Previous studies with hypertriglyceridemic APOC3 transgenic mice have suggested that apolipoprotein C-III (apoC-III) may inhibit either the apoE-mediated hepatic uptake of TG-rich lipoproteins and/or the lipoprotein lipase (LPL)-mediated hydrolysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65a1a6f7ebd79e175c843a41b2737412
https://pubmed.ncbi.nlm.nih.gov/11590213
https://pubmed.ncbi.nlm.nih.gov/11590213