Zobrazeno 1 - 5
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pro vyhledávání: '"L M Carruth"'
Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor
Publikováno v:
Journal of Biological Chemistry. 266:12162-12167
Interleukin (IL) 1 alpha is synthesized as a 33-kDa precursor that is enzymatically cleaved to the 15-17-kDa forms that are found in the culture supernatants of activated macrophages. We have explored the possibility that calcium might enhance IL-1 p
Publikováno v:
The Journal of Immunology. 144:170-174
The concept of a membrane form of IL-1 arose from the observation that paraformaldehyde-treated macrophages display IL-1 bioactivity. Thus far, the biochemical characterization of a membrane form of the molecule has not been reported. In a recent pub
Autor:
Richard Kowalski, A. Zeevi, K. Raza, Kenneth R. McCurry, J. Britz, L. M. Carruth, Diana Zaldonis, Julie B. Woodcock, Kathy Spichty, Shahid Husain
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7(2)
Profound T-cell depletion with the monoclonal antibody alemtuzumab facilitates reduced maintenance immunosuppression in abdominal and lung transplantation. While the phenotype of the post-depletional T cells has been characterized, little is known ab
Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor
Publikováno v:
The Journal of biological chemistry. 266(19)
Interleukin (IL) 1 alpha is synthesized as a 33-kDa precursor that is enzymatically cleaved to the 15-17-kDa forms that are found in the culture supernatants of activated macrophages. We have explored the possibility that calcium might enhance IL-1 p
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(1)
The concept of a membrane form of IL-1 arose from the observation that paraformaldehyde-treated macrophages display IL-1 bioactivity. Thus far, the biochemical characterization of a membrane form of the molecule has not been reported. In a recent pub