Zobrazeno 1 - 8
of 8
pro vyhledávání: '"L M Bendhack"'
Publikováno v:
Journal of molecular and cellular cardiology. 122
To investigate the molecular mechanisms and cellular signaling pathways involved in the activation of TP receptors and the consequent induction of contractile responses in coronary arteries of renal hypertensive (2K-1C) rats.The coronary perfusion pr
Publikováno v:
Scopus-Elsevier
Ca2+plays a major role in vascular contraction, and a defect in intracellular Ca2+regulation has been associated with increased vascular reactivity in hypertension. To test the hypothesis that the sarcoplasmic reticulum does not adequately buffer Ca2
Autor:
P I, Ceron, L M, Bendhack
Publikováno v:
General pharmacology. 31(2)
1. The aim of this study was to test the hypothesis that impaired calcium (Ca2+) recycling by sarcoplasmic reticulum (SR) Ca2+-ATPase takes place in aortae from 1 kidney-1 clip (1K-1C) hypertensive rats. 2. The contractile response elicited when Ca2+
Increased pH induces tension development in rat anococcygeus muscle by intracellular calcium release
Autor:
A F, Scannavino, L M, Bendhack
Publikováno v:
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 27(6)
The relationship between extracellular pH (pHe) alterations and muscle tension was studied in rat anococcygeus muscle. Increased cytosolic calcium levels induced smooth muscle contraction and increased tension. Extracellular alkalinization (pH 8.2) w
Autor:
A M, Oliveira, L M, Bendhack
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 316
In the rat anococcygeus muscle both dopamine and noradrenaline induced concentration-dependent contractile responses. The alpha 1-antagonist prazosin inhibited both dopamine and noradrenaline responses, whereas the alpha 2-antagonist yohimbine influe
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 19
The hypothesis that signal transduction mediated by platelet-derived growth factor (PDGF) and angiotensin II (Ang II) is altered in vascular smooth muscle (VSM) cells from the spontaneously hypertensive rat (SHR) was tested by measuring changes in th
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 11(2 Pt 2)
Stimulation of phosphatidylinositol metabolism by neurotransmitters produces diacylglycerol, an activator of protein kinase C, which may be involved in hormone-mediated contractions. We studied the effect of a tumor-promoting phorbol ester, 12-deoxyp
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 243(1)
The previous finding that converting enzyme inhibitors (CEIs) potentiate bradykinin (BK), but do not inhibit conversion of angiotensin (ANG) I in isolated vessels, was explored further in the rat perfused mesenteric vascular bed. To investigate wheth