Zobrazeno 1 - 10
of 42
pro vyhledávání: '"L M, Thurston"'
Autor:
Xiu-Jun Yu, Haixia Xie, Yan Li, Mei Liu, Ruhong Hou, Alexander V. Predeus, Blanca M. Perez Sepulveda, Jay C. D. Hinton, David W. Holden, Teresa L. M. Thurston
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT The injectisome encoded by Salmonella pathogenicity island 2 (SPI-2) had been thought to translocate 28 effectors. Here, we used a proteomic approach to characterize the secretome of a clinical strain of invasive non-typhoidal Salmonella ent
Externí odkaz:
https://doaj.org/article/9ff9398d46de4a18a5884c97770df61d
Autor:
Adrianna Aleksandrowicz, Rafał Kolenda, Karolina Baraniewicz, Teresa L. M. Thurston, Jarosław Suchański, Krzysztof Grzymajlo
Publikováno v:
Frontiers in Microbiology, Vol 14 (2024)
IntroductionMultidrug resistance in bacteria is a pressing concern, particularly among clinical isolates. Gram-negative bacteria like Salmonella employ various strategies, such as altering membrane properties, to resist treatment. Their two-membrane
Externí odkaz:
https://doaj.org/article/5a637529dc9441a3ac4d615b2c96709e
Autor:
Mirza S. Baig, Teresa L. M. Thurston, Rahul Sharma, Rajat Atre, Uzma Saqib, Rakhi Khabiya, Shreya Bharti, Chit L. Poh
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0133bfd967f44c7cb9d2700165432830
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/d34f5b7b93ff4d9c889ca2d17486e975
Autor:
Sajjan Rajpoot, Kishore K. Wary, Rachel Ibbott, Dongfang Liu, Uzma Saqib, Teresa L. M. Thurston, Mirza S. Baig
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The Toll-interleukin-1 Receptor (TIR) domain-containing adaptor protein (TIRAP) represents a key intracellular signalling molecule regulating diverse immune responses. Its capacity to function as an adaptor molecule has been widely investigated in re
Externí odkaz:
https://doaj.org/article/542f16155e9c4ca79f20441c409889c8
Autor:
Hazel Mak, Teresa L. M. Thurston
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Bacterial effector proteins, delivered into host cells by specialized multiprotein secretion systems, are a key mediator of bacterial pathogenesis. Following delivery, they modulate a range of host cellular processes and functions. Strong selective p
Externí odkaz:
https://doaj.org/article/1919730060d647c5a0f023f52198229a
Autor:
Teresa L. M. Thurston, Sophie A. Matthews, Elliott Jennings, Eric Alix, Feng Shao, Avinash R. Shenoy, Mark A. Birrell, David W. Holden
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Inflammatory caspases restrict microbial growth by inducing cytokine production and pyroptosis, but other caspase-induced mechanisms are thought to contribute. Here the authors use time-lapse microscopy of single cells to show that caspase1/11 has an
Externí odkaz:
https://doaj.org/article/3dcaf1a910524de0b958aea81b142880
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
Externí odkaz:
https://doaj.org/article/14a65166807f40328d644f0148111c3a
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT As key components of innate immune defense, macrophages are essential in controlling bacterial pathogens, including group A Streptococcus (GAS). Despite this, only a limited number of studies have analyzed the recovery of GAS from within hum
Externí odkaz:
https://doaj.org/article/ffab9758c9e641c7be7569313cf1184d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Schroeder, G N, Pearson, J S & Thurston, T L M 2021, ' Editorial: Bacterial effectors as drivers of human disease: models, methods, mechanisms ', Frontiers in Cellular and Infection Microbiology, vol. 11, 708228 . https://doi.org/10.3389/fcimb.2021.708228
Schroeder, G N, Pearson, J S & Thurston, T L M 2021, ' Editorial: Bacterial effectors as drivers of human disease: models, methods, mechanisms ', Frontiers in Cellular and Infection Microbiology, vol. 11, 708228 . https://doi.org/10.3389/fcimb.2021.708228
Bacteria colonise virtually all ecological niches on earth. To interact with their surroundings, they evolved sophisticated multi-protein secretion systems that transport proteins, called effectors, from the bacterial cytoplasm into the extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85061c272f19cea1ef52b5652f9a5275
http://hdl.handle.net/10044/1/90663
http://hdl.handle.net/10044/1/90663