Zobrazeno 1 - 10
of 15
pro vyhledávání: '"L M, Schechtman"'
Publikováno v:
Mutation Research Letters. 142:127-131
Autor:
D. L. Putman, T. M. Anderson, George G. Hatch, R. E. Kouri, B. Most, R. A. Lubet, R. W. Nims, L. M. Schechtman, J. W. Cameron, Judson W. Spalding, Raymond W. Tennant
Publikováno v:
Environmental Mutagenesis. 8:515-531
Twelve chemicals from diverse structural classes were tested under code for their capacity to enhance the transformation of Syrian hamster embryo cells by simian adenovirus SA7 in two independent laboratories. Pretreatment of hamster cells with eight
Autor:
R. A. Lubet, R. E. Kouri, T. M. Anderson, L. M. Schechtman, J. W. Cameron, D. L. Putman, R. W. Nims, George G. Hatch, Judson W. Spalding, Raymond W. Tennant
Publikováno v:
Environmental Mutagenesis. 8:495-514
The intralaboratory and interlaboratory reproducibility of a DNA virus (SA7) transformation enhancement assay was investigated using nine carcinogenic and noncarcinogenic compounds representing a variety of chemical classes. By the use of standardize
Publikováno v:
Journal of Tissue Culture Methods. 10:179-183
A method for measuring the ability of chemicals to enhance focus formation by the highly oncogenic DNA-containing simian adenovirus SA7 is described. The standard test consists of a) pretreatment of target Syrian hamster embryo cells with chemical te
Publikováno v:
Environmental Mutagenesis. 5:227-231
Di-(2-ethylhexyl)phthalate (DEHP) and its two major metabolites, mono-(2-ethylhexyl)phthalate (MEHP) and 2-ethylhexanol (EH), were evaluated for their ability to induce chromosomal damage in male Fischer 344 rats after oral administration. Dose level
Autor:
C, Heidelberger, A E, Freeman, R J, Pienta, A, Sivak, J S, Bertram, B C, Casto, V C, Dunkel, M W, Francis, T, Kakunaga, J B, Little, L M, Schechtman
Publikováno v:
Mutation research. 114(3)
The literature on cell transformation by chemical carcinogens has been critically reviewed. This subject is highly relevant to carcinogenesis in vivo, because the phenotypic changes that are collectively referred to as cell transformation usually inv
Autor:
L M, Schechtman
Publikováno v:
IARC scientific publications. 67
Publikováno v:
Cancer research. 39(5)
Several in vitro phenotypic characteristics frequently associated with neoplastic cells were examined in a series of spontaneous and benzo(a)pyrene-induced Syrian hamster clonal cell lines which differed in their degree of tumorigenicity. Nonparametr
Autor:
L M, Schechtman
Publikováno v:
IARC scientific publications. 67
Publikováno v:
Journal of the National Cancer Institute. 71(5)
The standard C3H/10T1/2 clone 8 (C3H/10T1/2 CL8) cell transformation assay was tested for its ability to identify a variety of polycyclic hydrocarbons and alkylating agents. Dose-dependent morphologic transformation occurred with benzo[a]pyrene (BaP)