Zobrazeno 1 - 10
of 44
pro vyhledávání: '"L M, Rose"'
Publikováno v:
Rheumatology. 34:316-320
It has been postulated that the high levels of autoantibodies observed in systemic lupus erythematosus (SLE) patients could result from abnormal longevity of polyclonally activated B-cells. This increased survival could be due to dysfunction of apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c8398a7c7fbca40b9c513ca7579aa3
https://doi.org/10.1093/rheumatology/34.4.316
https://doi.org/10.1093/rheumatology/34.4.316
Publikováno v:
Magnetic Resonance in Medicine. 29:478-484
Diffusion-weighted magnetic resonance imaging (MRI) was compared with T2-weighted MRI in longitudinal studies of experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis, in five monkeys (Macaca fascicularis). In a region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c8877a5f3dafcec9ad75dda6abdd97
https://doi.org/10.1002/mrm.1910290409
https://doi.org/10.1002/mrm.1910290409
Autor:
W B, Parker, S C, Shaddix, L M, Rose, D S, Shewach, L W, Hertel, J A, Secrist, J A, Montgomery, L L, Bennett
Publikováno v:
Molecular pharmacology. 55(3)
In an effort to understand biochemical features that are important to the selective antitumor activity of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine [Cl-F( upward arrow)-dAdo], we evaluated the biochemical pharmacology of three stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b4d7445517df705c9b947bfadebfc66
https://pubmed.ncbi.nlm.nih.gov/10051535
https://pubmed.ncbi.nlm.nih.gov/10051535
Publikováno v:
British journal of rheumatology. 36(2)
There is increasing evidence to suggest that abnormalities in apoptosis may play a part in the pathogenesis of systemic lupus erythematosus (SLE). For example, there is now considerable evidence that bcl-2 expression is enhanced in a proportion of pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bf6a7f843a006a918f3d840cc81ee7
https://pubmed.ncbi.nlm.nih.gov/9133921
https://pubmed.ncbi.nlm.nih.gov/9133921
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0f5b33e4a856645598299c1a5856b45
https://pubmed.ncbi.nlm.nih.gov/7493557
https://pubmed.ncbi.nlm.nih.gov/7493557
Autor:
J Peterson, S Cosgrove, Y He, Aaron C. Heide, Kenneth I. Marro, Ellsworth C. Alvord, K Petersen, Todd L. Richards, L. M. Rose
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 1(2)
Diffusion imaging and T2-weighted magnetic resonance imaging were performed on 16 monkeys with experimental allergic encephalomyelitis (EAE), a model of the human demyelinating disease MS. The purpose of this study was to determine whether local chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bfd2ad1a5aa358dfb74ac04e16cefb
https://pubmed.ncbi.nlm.nih.gov/9345461
https://pubmed.ncbi.nlm.nih.gov/9345461
Publikováno v:
Laboratory animal science. 44(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7e9c2d4775a32958678ee0770826541
https://pubmed.ncbi.nlm.nih.gov/7844962
https://pubmed.ncbi.nlm.nih.gov/7844962
Autor:
L L, Bennett, W B, Parker, P W, Allan, L M, Rose, Y F, Shealy, J A, Secrist, J A, Montgomery, G, Arnett, R L, Kirkman, W M, Shannon
Publikováno v:
Molecular pharmacology. 44(6)
CdG, the carbocyclic analog of 2'-deoxyguanosine, is active against herpes, hepatitis B, and human cytomegaloviruses. We have studied the interaction of the tritiated enantiomers of CdG with the herpes simplex virus type 1-specific thymidine kinase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b42ecce0509fc371e75732c37714bb8
https://pubmed.ncbi.nlm.nih.gov/8264563
https://pubmed.ncbi.nlm.nih.gov/8264563
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(2)
Certain derivatives of 9-deazaguanine that contain arylmethyl, heteroarylmethyl or cycloalkylmethyl groups at the 9-position are potent inhibitors of purine nucleoside phosphorylase (PNP, E.C. 2.4.2.1). To determine whether these agents can produce m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adfa2d0ba5e539c546165e2d4ad60138
https://pubmed.ncbi.nlm.nih.gov/8355201
https://pubmed.ncbi.nlm.nih.gov/8355201
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(2)
This study was undertaken to evaluate the disposition of the thiazolobenzimidazole, 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole (TZB), which has promising antiviral activity. For mice, the maximum tolerated intravenous dose of TZB was 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60a6bb3c3ae9fc1fd9f8d45580e12684
https://pubmed.ncbi.nlm.nih.gov/8097690
https://pubmed.ncbi.nlm.nih.gov/8097690