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pro vyhledávání: '"L M, Piliero"'
Autor:
M. Petri, Kathleen E. Sullivan, X. Luan, L. M. Piliero, Nahmah A. Kim, Abbas F. Jawad, Daniel Goldman
Publikováno v:
Rheumatology (Oxford, England). 42(3)
Objectives. Systemic lupus erythematosus (SLE) is a polygenic disorder of dysregulated inflammation. Numerous specific candidate genes have been identified and most relate to the handling of immune complexes or antigen presentation. This is consisten
Publikováno v:
Genes and immunity. 2(5)
Interferon-gamma is a cytokine which is believed to play a role in both the susceptibility and pathogenesis of lupus. To determine whether genetic variants might influence the development of this polygenic autoimmune disease, we analyzed the gene fre
Publikováno v:
Human mutation. 16(1)
A microsatellite repeat polymorphism was identified in the 3' flanking region of the human ETS1 gene. Sequencing revealed two CA repeat segments in close proximity. Seven different alleles comprising various combinations of CA repeat units were ident