Výsledky vyhledávání - "L M, Pawella"

SY14-4PRIMARY HEPATOCELLULAR DAMAGE AND SUPPRESSED FAT MOBILIZATION IN HEAVY DRINKERS WITH PNPLA3 G GENOTYPE

Autor: Carolin Lackner, Thomas Longerich, Teresa Peccerella, Helmut-Karl Seitz, S. Herzig, Beate K. Straub, Vanessa Rausch, Eray Yagmur, Sebastian Mueller, Felix Stickel, L. M. Pawella

Publikováno v: Rausch, V.; Straub, Katharina B.; Peccerella, T.; Pawella, L. M.; Lackner, C.; Yagmur, Eray; Stickel, Felix; Herzig, S.; Seitz, H.K.; Longerich, T.; Mueller, S. (2015). SY14-4PRIMARY HEPATOCELLULAR DAMAGE AND SUPPRESSED FAT MOBILIZATION IN HEAVY DRINKERS WITH PNPLA3 G GENOTYPE. Alcohol and alcoholism, 50(suppl 1), i17.1-i17. Oxford University Press 10.1093/alcalc/agv076.59

PNPLA3 GG genotype has been identified as important progression factor in patients with ALD and NAFLD. Since PNPLA3 function remains poorly understood, we here studied genotype distribution and various noninvasive, serum and molecular markers of live

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62b857764e6bffd04c6bb3b5376ff9a
http://doc.rero.ch/record/298418/files/agv076.59.pdf

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[Lipid droplet-associated proteins in steatosis. Effects of induction and siRNA-mediated downregulation of PAT proteins in cell culture models of hepatocyte steatosis]

Autor: L M, Pawella, M, Hashani, P, Schirmacher, B K, Straub

Publikováno v: Der Pathologe. 31

The accumulation of hepatocellular lipid droplets, referred to as steatosis, is the most frequent liver pathology in western industrial countries. The surface of lipid droplets is stabilized by amphiphilic proteins of the PAT family (perilipin, adipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d484ce30d88a39d3dbf0c754306822ae
https://pubmed.ncbi.nlm.nih.gov/20661576

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P1124 : Primary hepatocellular damage lowers alcohol consumption and suppresses peripheral fat mobilization in ALD patients with genetic variant I148M in PNPLA3

Autor: Helmut-Karl Seitz, K. Lackner, Sebastian Mueller, Felix Stickel, Thomas Longerich, S. Herzig, L. M. Pawella, Vanessa Rausch, Eray Yagmur, Teresa Peccerella, Beate K. Straub

Publikováno v: Journal of Hepatology. 62:S772

P1123 A FUNCTIONAL VARIANT IN TM6SF2 ASSOCIATES WITH ALCOHOLRELATED CIRRHOSIS RISK IN A BRITISH AND IRISH POPULATION M.J. Way, S. Atkinson, A. McQuillin, M.R. Thursz, M.Y. Morgan. Institute for Liver and Digestive Health, Molecular Psychiatry, Univer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d1da014378840c036537fc00be3d91a
https://doi.org/10.1016/s0168-8278(15)31321-0

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