Zobrazeno 1 - 10
of 32
pro vyhledávání: '"L M, Gracheva"'
Autor:
S. V. Kovaltsova, L. M. Gracheva, D. V. Fedorov, T. A. Evstuhina, V. G. Korolev, A. Yu. Chernenkov, V. T. Peshekhonov, I. V. Fedorova
Publikováno v:
Russian Journal of Genetics. 48:284-290
It was assumed previously that the mutator phenotype of the hms3 mutant was determined by processes taking place in the D-loop. As a next step, genetic analysis was performed to study the interactions between the hsm3 mutation and mutations of the ge
Autor:
T. A. Evstyukhina, A. Yu. Chernenkov, L. M. Gracheva, I. V. Fedorova, V. G. Korolev, V. T. Peshekhonov, S. V. Kovaltsova
Publikováno v:
Russian Journal of Genetics. 48:139-145
In eukaryotes, damage tolerance of matrix DNA is mainly determined by the repair pathway under the control of the RAD6 epistatic group of genes. This pathway is also a main source of mutations generated by mutagenic factors. The results of our recent
Autor:
L. M. Gracheva, V. T. Peshekhonov, A. Yu. Chernenkov, S. V. Ivanova, I. V. Fedorova, S.V. Kovaltzova, V. G. Korolev
Publikováno v:
Russian Journal of Genetics. 46:652-658
Gene HSM3 encodes the Hsm3 protein involved in the minor branch in the system responsible for the correction of mismatched bases in DNA structure and controls replicative and reparative spontaneous mutagenesis in yeast Saccharomyces cerevisiae. Spont
Publikováno v:
Russian Journal of Genetics. 44:1272-1279
Geptrong is a medication from pure defermentated honey. In medical practice, it is used as hepatoprotector. Genotoxicity analysis revealed antimutagenic activity of the preparation. The spontaneous mutation rate at the ADE4-ADE8 and CAN1 loci was sev
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 554:67-75
In this work, we studied the influence of hsm3 mutation on spontaneous mutagenesis in actively and slowly dividing cells. We demonstrated that the spontaneous mutation rates in the hsm3 mutant and the wild type strain were similar in actively dividin
Autor:
Tatyana A. Evstuhina, Vladimir G. Korolev, Irina V. Fedorova, Svetlana V. Kovaltzova, L. M. Gracheva, Sergey Yu. Alekseev
Publikováno v:
Genetics. 148:963-973
Mutants with enhanced spontaneous mutability (hsm) to canavanine resistance were induced by N-methyl-N-nitrosourea in Saccharomyces cerevisiae. One bearing the hsm3-1 mutation was used for this study. This mutation does not increase sensitivity to th
Autor:
A Iu, Chernenkov, D V, Fedorov, L M, Gracheva, T A, Evstukhina, S V, Koval'tsova, V T, Peshekhonov, I V, Fedorova, V G, Korolev
Publikováno v:
Genetika. 48(3)
It was assumed previously that the mutator phenotype of the hms3 mutant was determined by processes taking place in the D-loop. As a next step, genetic analysis was performed to study the interactions between the hsm3 mutation and mutations of the ge
Autor:
A Iu, Chernenkov, L M, Gracheva, T A, Evstiukhina, S V, Koval'tsova, V T, Peshekhonov, I V, Fedorova, V G, Korolev
Publikováno v:
Genetika. 48(2)
In eukaryotes, damage tolerance of matrix DNA is mainly determined by the repair pathway under the control of the RAD6 epistatic group of genes. T this pathway is also a main source of mutations generated by mutagenic factors. The results of our rece
Autor:
A Iu, Chernenkov, S V, Ivanova, S V, Koval'tsova, L M, Gracheva, V T, Peshekhonov, I V, Fedorova, V G, Korolev
Publikováno v:
Genetika. 46(6)
Gene HSM3 encodes the Hsm3 protein involved in the minor branch in the system responsible for the correction of mismatched bases in DNA structure and controls replicative and reparative spontaneous mutagenesis in yeast Saccharomyces cerevisiae. Spont
Publikováno v:
Genetika. 44(11)
Geptrong is a medication from pure defermentated honey. In medical practice, it is used as hepatoprotector. Genotoxicity analysis revealed antimutagenic activity of the preparation. The spontaneous mutation rate at the ADE4-ADE8 and CAN1 loci was sev