Zobrazeno 1 - 6
of 6
pro vyhledávání: '"L M, Gaster"'
Autor:
Peter Ham, J V Selkirk, Frank E. Blaney, Susannah Davies, L M Gaster, David Malcolm Duckworth, John M. Hatcher, Derek N. Middlemiss, Gary W. Price, Frank King, P. D. Slade, Jim J. Hagan, Wyman Paul Adrian, Graham Francis Joiner, Claire Roberts, Sarah Margaret Jenkins, Carol Routledge, Keith Raymond Mulholland, Riley Gj, Andrew John Jennings, B. J. Jones
Publikováno v:
Journal of Medicinal Chemistry. 41:1218-1235
5-HT1 receptors are members of the G-protein-coupled receptor superfamily and are negatively linked to adenylyl cyclase activity. The human 5-HT1B and 5-HT1D receptors (previously known as 5-HT1Dbeta and 5-HT1Dalpha, respectively), although encoded b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0abdd93d86c3590513d6f50b8ec21a9
https://doi.org/10.1021/jm970457s
https://doi.org/10.1021/jm970457s
Autor:
Keith Raymond Mulholland, E.S. Ellis, S Starr, Andrew John Jennings, Wyman Paul Adrian, L M Gaster, Frank King, Graham Francis Joiner, Kay A. Wardle, Sh K Rahman
Publikováno v:
Journal of Medicinal Chemistry. 36:4121-4123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef304443d22d699a5a9efced745d625
https://doi.org/10.1021/jm00077a018
https://doi.org/10.1021/jm00077a018
Autor:
Stephen E. Clarke, G. E. Jones, Steven Mark Bromidge, David T. Davies, Wyman Paul Adrian, Peter Ham, Sean Lightowler, Derek N. Middlemiss, Saunders Dv, Brenda K. Trail, Holland, Keith Raymond Mulholland, Ian Thomson Forbes, Frank E. Blaney, Riley Gj, Thomas P. Blackburn, David Malcolm Duckworth, Guy A. Kennett, Steven Dabbs, Susannah Davies, L M Gaster, Frank King, Wood
Publikováno v:
Journal of medicinal chemistry. 43(6)
The evolution, synthesis, and biological activity of a novel series of 5-HT(2C) receptor inverse agonists are reported. Biarylcarbamoylindolines have been identified with excellent 5-HT(2C) affinity and selectivity over 5-HT(2A) receptors. In additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b2c4d295fb2cd0d97e112ed3e2e458
https://pubmed.ncbi.nlm.nih.gov/10737744
https://pubmed.ncbi.nlm.nih.gov/10737744
Autor:
J V, Selkirk, C, Scott, M, Ho, M J, Burton, J, Watson, L M, Gaster, L, Collin, B J, Jones, D N, Middlemiss, G W, Price
Publikováno v:
British journal of pharmacology. 125(1)
1. Human 5-HT1B (h5-HT1B) and human 5-HT1D (h5-HT1D) receptors show remarkably similar pharmacology with few compounds discriminating the receptors. We report here on a novel compound, SB-224289 (1'-Methyl-5-[[2'-methyl-4'-(5-methyl- 1,2,4-oxadiazol-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2438d5e28575e7c3d7fafb2d9f0c69bb
https://pubmed.ncbi.nlm.nih.gov/9776361
https://pubmed.ncbi.nlm.nih.gov/9776361
Autor:
L M, Gaster, F D, King
Publikováno v:
Medicinal research reviews. 17(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bf4ab5730107cfb8b0d250cb2014acc
https://pubmed.ncbi.nlm.nih.gov/9057164
https://pubmed.ncbi.nlm.nih.gov/9057164
Autor:
C. J. Rose, L. M. Gaster, A. C. Goudie, A. W. Lake, P. C. Freeman, B. O. Hughes, David Miller
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83cd9852689b49bb766919dfc6cc1a1c
https://doi.org/10.1002/chin.197918219
https://doi.org/10.1002/chin.197918219