Zobrazeno 1 - 10
of 13
pro vyhledávání: '"L Leonie van Leeuwen"'
Autor:
Ceilidh McKenney, Julia Torabi, Rachel Todd, M. Zeeshan Akhtar, Fasika M. Tedla, Ron Shapiro, Sander S. Florman, Matthew L. Holzner, L. Leonie van Leeuwen
Publikováno v:
Transplantology, Vol 5, Iss 2, Pp 51-64 (2024)
Kidney transplantation is a life-saving intervention for end-stage renal disease; yet, the persistent gap between organ demand and supply remains a significant challenge. This paper explores the escalating discard rates of deceased donor kidneys in t
Externí odkaz:
https://doaj.org/article/6741d89d545b4fb18a49980e610279d0
Autor:
Julia Torabi, MD, Rachel Todd, BA, L. Leonie van Leeuwen, PhD, Yuki Bekki, MD, Matthew Holzner, MD, Jang Moon, MD, Tom Schiano, MD, Sander S. Florman, MD, Mohammed Zeeshan Akhtar, BM, BCh, FRCS
Publikováno v:
Transplantation Direct, Vol 10, Iss 6, p e1605 (2024)
Background:. Organ shortage remains a major challenge for the field of transplantation. Maximizing utilization and minimizing discard of available organs is crucial to reduce waitlist times. Our aim was to investigate the landscape of liver recovery,
Externí odkaz:
https://doaj.org/article/f4642bc408644494b12f073528e3f6cd
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5437-5459 (2023)
Recently, immense efforts have focused on improving the preservation of (sub)optimal donor organs by means of ex vivo perfusion, which enables the opportunity for organ reconditioning and viability assessment. However, there is still no biomarker tha
Externí odkaz:
https://doaj.org/article/14eb60dddb62421bbc948f319fd0cc63
Publikováno v:
Transplantology, Vol 4, Iss 2, Pp 59-70 (2023)
Circulatory death donor (DCD) kidneys are increasingly used to enlarge the donor pool. These kidneys undergo ischemia-reperfusion injury, frequently leading to renal fibrosis. Transforming growth factor beta 1 (TGF-β1) and matrix metalloproteases ha
Externí odkaz:
https://doaj.org/article/a48f5bf1dff04ea0bdb166f4fc07c240
Autor:
L. Annick van Furth, Henri G. D. Leuvenink, Lorina Seras, Inge A. M. de Graaf, Peter Olinga, L. Leonie van Leeuwen
Publikováno v:
Transplantology, Vol 3, Iss 2, Pp 139-151 (2022)
Marginal donor kidneys are more likely to develop ischemia-reperfusion injury (IRI), resulting in inferior long-term outcomes. Perfusion techniques are used to attenuate IRI and improve graft quality. However, machine perfusion is still in its infanc
Externí odkaz:
https://doaj.org/article/d376b6d975f0454890e5b6ca84bf75b3
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Great efforts have been made toward addressing the demand for donor kidneys. One of the most promising approaches is to use kidneys from donation after circulatory death donors. These kidneys, however, suffer from more severe ischemia and reperfusion
Externí odkaz:
https://doaj.org/article/05e3156b846f44609009e9069b713f78
Autor:
L. Leonie van Leeuwen, Henri G.D. Leuvenink, Benedikt M. Kessler, Peter Olinga, Mitchel J.R. Ruigrok
Normothermic machine perfusion is an emerging preservation technique for kidney allografts to reduce post-transplant complications, including interstitial fibrosis and tubular atrophy. This technique, however, could be improved by adding antifibrotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc8bcc4d1b940e4a8369186015b1fe4
https://doi.org/10.1101/2022.03.22.485255
https://doi.org/10.1101/2022.03.22.485255
Autor:
L. Annick van Furth, Tobias M Huijink, Hanno Maassen, L. Leonie van Leeuwen, Veerle A Lantinga, Baran Ogurlu, Tim L Hamelink, Merel B F Pool, Rianne Schutter, Cyril Moers, Henri G D Leuvenink, Rene A Posma, Leonie H Venema
Publikováno v:
Transplantation. 106:S217-S217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d40629d4f178bc445b46e5c36c57e45
https://doi.org/10.1097/01.tp.0000886480.53828.39
https://doi.org/10.1097/01.tp.0000886480.53828.39
Autor:
Honglei Huang, Bas W M van Balkom, Adam M. Thorne, Rutger J. Ploeg, Sarah Bonham, Henri G. D. Leuvenink, L Leonie van Leeuwen, Nora A Spraakman, Aukje Brat, Benedikt M. Kessler
Publikováno v:
Transplant International, 34(9), 1618-1629. Wiley
Assessment of donor kidney quality is based on clinical scores or requires biopsies for histological assessment. Noninvasive strategies to identify and predict graft outcome at an early stage are, therefore, needed. We evaluated the perfusate of dona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffff8f2a7d4481fb9e602ac32825243
https://pubmed.ncbi.nlm.nih.gov/34448265
https://pubmed.ncbi.nlm.nih.gov/34448265
Publikováno v:
Transplantation. 104:S178-S178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00b88913d064cb1110e75c396a8c921f
https://doi.org/10.1097/01.tp.0000699260.80138.c8
https://doi.org/10.1097/01.tp.0000699260.80138.c8