Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L L Rokosz"'
Autor:
L L Rokosz, J J Burbaum, Janey N. Parsons, Scott P. Salowe, Gregory J. Wiederrecht, Stephen J. O'Keefe, R L Kincaid
Publikováno v:
Journal of Biological Chemistry. 269:19610-19616
The immunosuppressant FK-506 (tacrolimus) forms a complex with a ubiquitous intracellular receptor, FK-506 binding protein (FKBP12), and this complex inhibits the heterodimeric Ca2+/calmodulin-dependent phosphatase, calcineurin, an essential componen
Autor:
J N, Parsons, G J, Wiederrecht, S, Salowe, J J, Burbaum, L L, Rokosz, R L, Kincaid, S J, O'Keefe
Publikováno v:
The Journal of biological chemistry. 269(30)
The immunosuppressant FK-506 (tacrolimus) forms a complex with a ubiquitous intracellular receptor, FK-506 binding protein (FKBP12), and this complex inhibits the heterodimeric Ca2+/calmodulin-dependent phosphatase, calcineurin, an essential componen
Autor:
L. L. Rokosz, P. A. Lachance, Gautam Sanyal, M. A. Cueto, E. A. Butkiewicz, D. A. Boulton, J. D. Hermes
Publikováno v:
Archives of biochemistry and biophysics. 312(1)
A cDNA for the human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (EC 4.1.3.5) was subcloned and expressed from a T7-based vector in Escherichia coli. The over-produced enzyme was purified using a three-step protocol that gene