Zobrazeno 1 - 10
of 134
pro vyhledávání: '"L L Lanier"'
Autor:
M. Cella, M. Colonna, Adrian Hayday, C. Reis e Sousa, L. L. Lanier, Gordon D. Brown, K. Otero, Shigeo Koyasu
Publikováno v:
International Immunology. 22:ii1-ii3
Publikováno v:
The Journal of Immunology. 158:5237-5241
Allotypes from four divergent HLA-B families (B8, B15, B16, and B27) were compared for their inhibition of cytolysis by NK cells expressing the NKB1 receptor. Allotypes differing solely at the Bw4/Bw6 region were examined as were a more divergent sub
Publikováno v:
The Journal of Immunology. 158:3603-3609
NKG2 is a small family of type II transmembrane proteins possessing extracellular C-type lectin domains expressed primarily on NK cells. The function of these proteins is unknown. We have developed mAbs that recognize NKG2 family members on Western b
Publikováno v:
The Journal of Immunology. 157:4741-4745
CD94 receptors expressed on NK cells have been implicated in the recognition of certain HLA class I allotypes. We now demonstrate that CD94 glycoproteins form disulfide-bonded heterodimers with the NKG2A/B, NKG2C, and NKG2E glycoproteins. NKG2A/B pos
Publikováno v:
The Journal of Immunology. 156:3254-3259
IL-15 is a newly described cytokine produced by monocytes and other non-T cells that utilizes the IL-2R beta- and common gamma-chains, thereby stimulating many NK cell functions previously ascribed to IL-2. Thus, IL-15 may promote NK cell activity du
Publikováno v:
The Journal of Immunology. 155:2306-2310
The expression of certain MHC class I allotypes by potential target cells can inhibit NK cell-mediated cytotoxicity. We recently identified the NKB1 surface Ag, expressed on T and NK cell subsets, as a putative inhibitory receptor for HLA-B class I m
Publikováno v:
The Journal of Immunology. 153:2417-2428
In rodents, the NKR-P1 family of glycoproteins are preferentially expressed on NK cells and have been implicated in NK cell function. In this study, we describe the characterization and cloning of a human homologue. Human (h)NKR-P1A cDNA was cloned f
Publikováno v:
The Journal of Immunology. 152:1523-1531
CD40 is a membrane differentiation antigen constitutively expressed on B cells that induces B cell growth and Ig synthesis after ligation with anti-CD40 mAb or with the recently identified CD40 ligand (CD40L). CD40L is rapidly induced on T cells afte
Publikováno v:
The Journal of Immunology. 150:1147-1159
A subset of CD8+ alpha beta-TCR/CD3+ T lymphocytes in adult human peripheral blood lacks expression of CD28, a membrane receptor for the B7/BB1 B cell differentiation Ag that is involved in T cell activation. CD28-8+ T cells were not observed in the
Publikováno v:
The Journal of Immunology. 147:3459-3465
Two genes encode the CD16 low affinity IgG FcR. CD16-I (Fc gamma RIII-1) is expressed on PMN as a phosphatidylinositol-glycan anchored glycoprotein. CD16-II (Fc gamma RIII-2) is expressed on NK cells and macrophages as a transmembrane glycoprotein as