Zobrazeno 1 - 10
of 85
pro vyhledávání: '"L L Brunton"'
Publikováno v:
Journal of Biological Chemistry. 265:15076-15082
In this study we examined the effects of insulin on protein kinase C (PKC) activity in cultured fetal chick neurons. PKC activity, measured as 32P incorporation into histone H1 in the presence of calcium (500 microM), phosphatidylserine (100 microgra
Publikováno v:
Journal of Biological Chemistry. 265:12248-12252
We have evaluated potential molecular mechanisms by which a group of synthetic lymphokine-like molecules, the 7,8-disubstituted guanine ribonucleosides, acts on second messenger pathways to augment the responses of murine B lymphocytes. Despite its e
Publikováno v:
The Journal of Immunology. 144:3592-3601
IL-7 cDNA clones were used to isolate clones from the human IL-7 gene locus. Characterization of the clones revealed that the human IL-7 gene contains six exons, distributed over more than 33-kbp. An 18 amino acid insert found in human IL-7, for whic
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
In experiments on neonatal and adult rat ventricular myocytes, endothelin (ET) binding and the effects of ET on transmembrane signaling are quasi-irreversible. The ET(A) receptor antagonist BQ123 competes for binding and biochemical effects if added
Publikováno v:
The Journal of biological chemistry. 269(24)
We have immunologically identified the isoforms of protein kinase C (PKC) present in neonatal and adult rat cardiomyocytes and examined their regulation by hormones and phorbol ester. Both cell types express the Ca(2+)-dependent alpha-PKC and the Ca(
Publikováno v:
The Journal of biological chemistry. 265(25)
In this study we examined the effects of insulin on protein kinase C (PKC) activity in cultured fetal chick neurons. PKC activity, measured as 32P incorporation into histone H1 in the presence of calcium (500 microM), phosphatidylserine (100 microgra
Publikováno v:
The Journal of biological chemistry. 265(21)
We have evaluated potential molecular mechanisms by which a group of synthetic lymphokine-like molecules, the 7,8-disubstituted guanine ribonucleosides, acts on second messenger pathways to augment the responses of murine B lymphocytes. Despite its e
Publikováno v:
Molecular pharmacology. 37(4)
The time course of cAMP production by S49 cell membranes in the presence of forskolin and a nonhydrolyzable GTP analog can yield information about the regulation of adenylate cyclase by both the inhibitory and stimulatory GTP-binding proteins (Gi and
Autor:
L. L. Brunton
Publikováno v:
Science Signaling. 2003:pe44-pe44
Publikováno v:
Journal of Biological Chemistry. 251:3037-3044
A method for assessing the binding of 3H-labeled prostaglandin E1 ([3H]PGE1) to cell membranes has been developed and used to study the interaction of [3H]PGE1 with membranes from cultured mammalian cells. Receptor sites were identified by correlatio