Zobrazeno 1 - 10
of 105
pro vyhledávání: '"L L, Moldawer"'
Autor:
L. L. Moldawer, S. F. Lowry
Publikováno v:
Nutrient Modulation of the Immune Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4319b3f66ab07fa36eb6ee5302a27847
https://doi.org/10.1201/9781003066644-38
https://doi.org/10.1201/9781003066644-38
Autor:
L. L. Moldawer, C. A. Benbassat, S. B. Cichy, D. D. Lazarus, S. F. Lowry, Terry G. Unterman, T. M. Evans
Publikováno v:
Hormone and Metabolic Research. 31:209-215
TNF alpha and IL-1 alpha are thought to contribute to impaired anabolism in a variety of clinical states, including sepsis, cancer cachexia and the AIDS wasting syndrome. We asked whether cytokines exert direct effects on hepatic production of IGFBP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13d576cd4da2bfbf63273080cd9510c
https://doi.org/10.1055/s-2007-978721
https://doi.org/10.1055/s-2007-978721
Autor:
C C Solorzano, R Ksontini, J H Pruitt, P J Hess, P D Edwards, A Kaibara, A Abouhamze, T Auffenberg, R E Galardy, J N Vauthey, E M Copeland, C K Edwards, G Y Lauwers, M Clare-Salzler, S L MacKay, L L Moldawer, D D Lazarus
Publikováno v:
The Journal of Immunology. 158:414-419
TNF-alpha is a pleiotropic cytokine that exists both as a 26-kDa cell-associated and a 17-kDa soluble form. Recently, a class of matrix metalloproteinase inhibitors has been identified that can prevent the processing by TNF convertase of 26-kDa TNF-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbbc678427a25e7f740e538ac6396479
https://doi.org/10.4049/jimmunol.158.1.414
https://doi.org/10.4049/jimmunol.158.1.414
Publikováno v:
Journal of infectious diseases, 174(6), 1356-1360. Oxford University Press
Whole blood of 6 healthy subjects, who were intravenously injected with lipopolysaccharide (LPS, 2 ng/kg), was stimulated ex vivo with LPS (10 ng/mL). Three and 6 h after injection of LPS, whole blood produced less tumor necrosis factor-alpha (TNF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e0a36d7a319a64cd6edab68ac80b86
https://doi.org/10.1093/infdis/174.6.1356
https://doi.org/10.1093/infdis/174.6.1356
Autor:
Stephen F. Lowry, C. C. Braxton, K. Barbosa, T van der Poll, Steven E. Calvano, L. L. Moldawer, S. M. Coyle, Ashwini Kumar
Publikováno v:
Blood, 86(7), 2754-2759. American Society of Hematology
Leukocytes rapidly lose their surface receptors for tumor necrosis factor (TNF) after exposure to various stimuli in vitro. To assess the effect of endotoxin on cellular TNF receptors in humans in vivo, binding of biotinylated TNF to circulating mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4e15bd8beee72ba4aa6139ce5af362
https://doi.org/10.1182/blood.v86.7.2754.2754
https://doi.org/10.1182/blood.v86.7.2754.2754
Autor:
T, van der Poll, S E, Calvano, A, Kumar, C C, Braxton, S M, Coyle, K, Barbosa, L L, Moldawer, S F, Lowry
Publikováno v:
Blood. 86:2754-2759
Leukocytes rapidly lose their surface receptors for tumor necrosis factor (TNF) after exposure to various stimuli in vitro. To assess the effect of endotoxin on cellular TNF receptors in humans in vivo, binding of biotinylated TNF to circulating mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fc2287664326bf0ad44cb0262dd848
https://doi.org/10.1182/blood.v86.7.2754.bloodjournal8672754
https://doi.org/10.1182/blood.v86.7.2754.bloodjournal8672754
Autor:
I. W. De Jong, T. van der Poll, Marja A. Boermeester, E Fischer, C. E. Hack, S. F. Lowry, P. M. Jansen, L. L. Moldawer
Publikováno v:
Blood. 86:1027-1034
Although studies with interleukin-1 receptor antagonist (IL-1ra) in animal models have shown that IL-1 contributes to mortality in sepsis, the mechanisms whereby IL-1 mediates lethal effects are not well established. A possible mechanism is that IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e2fc3720cd6a72de76c0abd975e519
https://doi.org/10.1182/blood.v86.3.1027.1027
https://doi.org/10.1182/blood.v86.3.1027.1027
Publikováno v:
The Journal of Immunology. 153:768-775
TNF-alpha has been implicated in cytokine-induced macrophage activation and tissue granuloma formation, two activities linked to control of intracellular visceral infection caused by Leishmania donovani. To determine the role of TNF-alpha in L. donov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693a663ee6ec3576c6572b0f75bd1aa7
https://doi.org/10.4049/jimmunol.153.2.768
https://doi.org/10.4049/jimmunol.153.2.768
Autor:
Marian N. Marra, Hester S. A. Oldenburg, Kimberly J. Van Zee, Steven E. Calvano, Randy W. Scott, L. L. Moldawer, S A Stackpole, W. J. Montegut, Michael A. Rogy, Stephen F. Lowry, Jeffrey J. Seilhammer
Publikováno v:
Journal of Clinical Immunology. 14:120-133
Human neutrophil azurophilic granules contain an approximately 55-kDa protein, known as bactericidal/permeability-increasing protein (BPI), which possesses a high-affinity binding domain for the lipid A component of lipopolysaccharide (LPS). The in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e32a6fa5dce80ac3826441a6de262
https://doi.org/10.1007/bf01541345
https://doi.org/10.1007/bf01541345
Autor:
Debra D. Poutsiaka, M. A. Marano, C S Rock, L. L. Moldawer, Stephen F. Lowry, K J Van Zee, JS Kenney, Charles A. Dinarello, E. Fischer
Publikováno v:
Blood. 79:2196-2200
Interleukin-1 receptor antagonist (IL-1ra) is a 22-Kd protein that shares homology with IL-1 beta, binds to the IL-1 receptor, but has no known agonist properties. This inhibitor appears to be the first cytokine whose sole function is to block the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::051b0ec58c57f5633ee3e829e3b41b03
https://doi.org/10.1182/blood.v79.9.2196.2196
https://doi.org/10.1182/blood.v79.9.2196.2196