Výsledky vyhledávání

BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production

Autor: J S, Kim-Han, S A, Reichert, K L, Quick, L L, Dugan

Publikováno v: Journal of neurochemistry. 79(3)

Outside the nervous system, members of the mitochondrial uncoupling protein (UCP) family have been proposed to contribute to control of body temperature and energy metabolism, and regulation of mitochondrial production of reactive oxygen species (ROS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fdd8a42db2a2bb22399852a89b90b671
https://pubmed.ncbi.nlm.nih.gov/11701769

Zobrazit plný text záznamu

Zinc-induced neuronal death in cortical neurons

Autor: D, Lobner, L M, Canzoniero, P, Manzerra, F, Gottron, H, Ying, M, Knudson, M, Tian, L L, Dugan, G A, Kerchner, C T, Sheline, S J, Korsmeyer, D W, Choi

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 46(4)

Although Zn2+ is normally stored and released in the brain, excessive exposure to extracellular Zn2+ can be neurotoxic. The purpose of the present study was to determine the type of neuronal cell death, necrosis versus apoptosis, induced by Zn2+ expo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a12d6d80ff71a066a8c65c1eaa06300b
https://pubmed.ncbi.nlm.nih.gov/10875441

Zobrazit plný text záznamu

Differential effects of cAMP in neurons and astrocytes. Role of B-raf

Autor: L L, Dugan, J S, Kim, Y, Zhang, R D, Bart, Y, Sun, D M, Holtzman, D H, Gutmann

Publikováno v: The Journal of biological chemistry. 274(36)

Mitogen-activated protein kinase (MAPK) activation provides cell type-specific signals important for cellular differentiation, proliferation, and survival. Cyclic AMP (cAMP) has divergent effects on MAPK activity depending on whether signaling is thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ce7cf88824d01c9f3fa11ccd4c78351
https://pubmed.ncbi.nlm.nih.gov/10464325

Zobrazit plný text záznamu

Neurotrophin-mediated potentiation of neuronal injury

Autor: M M, Behrens, U, Strasser, D, Lobner, L L, Dugan

Publikováno v: Microscopy research and technique. 45(4-5)

The neurotrophins are a diverse family of peptides which activate specific tyrosine kinase-linked receptors. Over the past five decades, since the pioneering work of Levi-Montalcini and colleagues, the critical role that neurotrophins play in shaping

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43453bc242b3d45efb47de38f2cf4d5e
https://pubmed.ncbi.nlm.nih.gov/10383120

Zobrazit plný text záznamu

Techniques for assessing neuroprotective drugs in vitro

Autor: M P, Goldberg, U, Strasser, L L, Dugan

Publikováno v: International review of neurobiology. 40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc05bec35a462f3dbbf27b7b7a73b56f
https://pubmed.ncbi.nlm.nih.gov/8989617

Zobrazit plný text záznamu

BDNF or IGF-I potentiates free radical-mediated injury in cortical cell cultures

Autor: B J, Gwag, J Y, Koh, M M, Chen, L L, Dugan, M M, Behrens, D, Lobner, D W, Choi

Publikováno v: Neuroreport. 7(1)

Free radical-mediated damage to cultured cortical neurons was induced by a 24 h exposure to Fe2+ (30 microM) or an inhibitor of gamma-glutamylcysteine synthetase, L-buthionine-[S,R]-sulfoximine (BSO, 1 mM). As expected, neuronal death was blocked by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6abf2256cfb3266d7f1276781e67f98
https://pubmed.ncbi.nlm.nih.gov/8742425

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání