Zobrazeno 1 - 10
of 31
pro vyhledávání: '"L L, Cummins"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 292(1)
Phosphorothioate antisense oligodeoxynucleotides are novel therapeutic agents designed to selectively and specifically inhibit production of various disease-related gene products. In vivo pharmacokinetic experiments indicate that these molecules are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c1b0eb2ac08fe33c45f23158745a06
https://pubmed.ncbi.nlm.nih.gov/10604941
https://pubmed.ncbi.nlm.nih.gov/10604941
Publikováno v:
Biotechnology and bioengineering. 61(3)
Capillary electrophoresis has been applied to monitor model reactions in solution-phase combinatorial chemistry. In particular, the simultaneous alkylation reactions of secondary amines with a series of benzyl halides has been investigated. Reactant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc355178937a7183e6f28331d23ddc33
https://pubmed.ncbi.nlm.nih.gov/10397804
https://pubmed.ncbi.nlm.nih.gov/10397804
Autor:
P L, Nicklin, D, Bayley, J, Giddings, S J, Craig, L L, Cummins, J G, Hastewell, J A, Phillips
Publikováno v:
Pharmaceutical research. 15(4)
Phosphorothioate antisense oligodeoxynucleotides are promising therapeutic candidates. When given systemically in clinical trials they are administered via slow intravenous infusion to avoid their putative plasma concentration-dependent haemodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa94d909cac89cf0081162d434cf304a
https://pubmed.ncbi.nlm.nih.gov/9587955
https://pubmed.ncbi.nlm.nih.gov/9587955
Publikováno v:
Journal of mass spectrometry : JMS. 32(3)
The pattern of nuclease degradation observed for an antisense phosphorothioate oligonucleotide in pig kidney was determined using liquid chromatography/electrospray mass spectrometry (LC/ESI-MS) and LC/ESI-MS/MS with a quadrupole ion trap mass spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21679b6d1c0b6411151619fa80f557eb
https://pubmed.ncbi.nlm.nih.gov/9075339
https://pubmed.ncbi.nlm.nih.gov/9075339
Autor:
S T, Crooke, M J, Graham, J E, Zuckerman, D, Brooks, B S, Conklin, L L, Cummins, M J, Greig, C J, Guinosso, D, Kornbrust, M, Manoharan, H M, Sasmor, T, Schleich, K L, Tivel, R H, Griffey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
Biophysical and pharmacokinetic properties of five analogs of ISIS 3082, a 20-mer phosphorothioate oligodeoxynucleotide that inhibits the expression of mouse intercellular adhesion molecule 1, were evaluated. Compared to the parent compound, ISIS 308
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d2defa0c01a053d57855b82849fe768
https://pubmed.ncbi.nlm.nih.gov/8627575
https://pubmed.ncbi.nlm.nih.gov/8627575
Autor:
Cummins L; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.; Princess Alexandra Hospital, Brisbane, Queensland, Australia., Katikireddi VS; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Shankaranarayana S; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Su KY; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Duggan E; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Videm V; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Immunology and Transfusion Medicine, St Olav University Hospital, Trondheim, Norway., Pahau H; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Thomas R; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.; Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Publikováno v:
Internal medicine journal [Intern Med J] 2015 Dec; Vol. 45 (12), pp. 1266-73.
Autor:
Douglas RM; Department of Pediatrics (Division of Respiratory Medicine), Albert Einstein College of Medicine, Bronx, NY 10461, USA., Lai JC, Bian S, Cummins L, Moczydlowski E, Haddad GG
Publikováno v:
Neuroscience [Neuroscience] 2006; Vol. 139 (4), pp. 1249-61. Date of Electronic Publication: 2006 Mar 29.
Publikováno v:
Nursing management [Nurs Manage] 1996 Oct; Vol. 27 (10), pp. 32B, 32F.