Zobrazeno 1 - 10
of 21
pro vyhledávání: '"L L, Christrup"'
Autor:
L L, Christrup
Publikováno v:
Acta Anaesthesiologica Scandinavica. 41:116-122
Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long-term treatment of severe pain. Morphine is a member of the morphinan-framed alkaloids, which are present in the poppy plant. The drug is soluble in water,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd42f5a9008cacc54ce8c0f01e7f4891
https://doi.org/10.1111/j.1399-6576.1997.tb04625.x
https://doi.org/10.1111/j.1399-6576.1997.tb04625.x
Autor:
T, Jonsson, L L, Christrup, J, Højsted, H H, Villesen, T H, Albjerg, L V, Ravn-Nielsen, P, Sjøgren
Publikováno v:
Acta anaesthesiologica Scandinavica. 55(1)
relieving distressing symptoms and managing the side effects of analgesics are essential in order to improve quality of life and functional capacity in chronic non-cancer pain patients. A quick, reliable and valid tool for assessing symptoms and side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d62fc3703b52eab70a657698c5d71f0
https://pubmed.ncbi.nlm.nih.gov/21039361
https://pubmed.ncbi.nlm.nih.gov/21039361
Autor:
H H, Villesen, D J R, Foster, R N, Upton, L L, Christrup, A A, Somogyi, A, Martinez, C, Grant
Publikováno v:
British journal of pharmacology. 149(6)
At present there are few data regarding the rate and extent of brain-blood partitioning of the opioid active metabolite of morphine, morphine-6-glucuronide (M6G). In this study the cerebral kinetics of M6G were determined, after a short-term intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3d0898347f912bab0ad56f04e5ccd08
https://pubmed.ncbi.nlm.nih.gov/17016501
https://pubmed.ncbi.nlm.nih.gov/17016501
Publikováno v:
Pharmacy worldscience : PWS. 23(5)
The aim of the study was to investigate the swallow ability and the patient preferences of tablets and capsules with different sizes, shapes, surfaces and colours.Patients were asked to swallow tablets with different surface and size, while tablets w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::401881afa14d4fe10aaa11d3562cc134
https://pubmed.ncbi.nlm.nih.gov/11721676
https://pubmed.ncbi.nlm.nih.gov/11721676
Publikováno v:
Acta anaesthesiologica Scandinavica. 45(6)
Gentamicin is used worldwide in the treatment of serious infections in critically ill patients. The therapeutic efficacy of gentamicin is correlated to the peak serum concentration and the adverse effects to the trough concentrations. Information con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb4f315e63da421b427163690e1d9ddd
https://pubmed.ncbi.nlm.nih.gov/11421832
https://pubmed.ncbi.nlm.nih.gov/11421832
Publikováno v:
Journal of pain and symptom management. 18(3)
Eighteen patients suffering from chronic pain due to cancer completed a balanced, double-blind, double-dummy, two period cross-over trial comparing the pharmacokinetics (PK) and pharmacodynamics (PD) of morphine and its metabolites, morphine-3-glucur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c05ebfe85eaa4c19644e68fbf2d71fd9
https://pubmed.ncbi.nlm.nih.gov/10517037
https://pubmed.ncbi.nlm.nih.gov/10517037
Publikováno v:
Ugeskrift for laeger. 159(22)
With the increasing use of morphine, growing interest for the clinical implications of its metabolites, morphine-3-glucuronide (M-3-G) and morphine-6-glucuronide (M-6-G) has emerged in the literature. M-6-G binds to the opioid receptor and has analge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9eed078cb8cd9bcab91812c25cbd684
https://pubmed.ncbi.nlm.nih.gov/9199024
https://pubmed.ncbi.nlm.nih.gov/9199024
Publikováno v:
Acta pharmaceutica Nordica. 4(4)
The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f76609d420799cfee2efe774b11e7d8
https://pubmed.ncbi.nlm.nih.gov/1294188
https://pubmed.ncbi.nlm.nih.gov/1294188
Publikováno v:
Acta pharmaceutica Nordica. 3(2)
Various carboxylic acid and carbonate esters of the opioid analgesic ketobemidone were prepared and assessed as potential prodrugs with the aim of obtaining a ketobemidone formulation suitable for buccal or sublingual absorption. The chemical stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::370c52fb82507667a2727b8d701935e7
https://pubmed.ncbi.nlm.nih.gov/1910550
https://pubmed.ncbi.nlm.nih.gov/1910550
Publikováno v:
Acta pharmaceutica Nordica. 3(4)
Chewing gum and lozenges were evaluated as delivery systems for noscapine with the aim of developing improved antitussive preparations. The formulations studied were prepared with both the water-soluble hydrochloride salt of noscapine and with the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c07919a39d387629c057014bd5784f83
https://pubmed.ncbi.nlm.nih.gov/1781914
https://pubmed.ncbi.nlm.nih.gov/1781914