Zobrazeno 1 - 10
of 1 186
pro vyhledávání: '"L Kung"'
Autor:
Rena Elkin, Jung Hun Oh, Filemon Dela Cruz, Larry Norton, Joseph O. Deasy, Andrew L. Kung, Allen R. Tannenbaum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Network properties account for the complex relationship between genes, making it easier to identify complex patterns in their interactions. In this work, we leveraged these network properties for dual purposes. First, we clustered pediatric
Externí odkaz:
https://doaj.org/article/1a3a594da4ab4acdaeb47f73b4300bb7
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
Neural epidermal growth factor-like 1 (NELL1) membranous nephropathy (MN) is notable for its segmental deposit distribution, IgG1 dominant deposits, and comparatively high rate of spontaneous remission. It has been associated with a variety of exposu
Externí odkaz:
https://doaj.org/article/906cd1a3989a4bfab540f54a07e4d732
Publikováno v:
Glomerular Diseases, Pp 1-1 (2024)
Introduction: Type 2 diabetes mellitus (DM) and diabetic kidney disease are increasing. Hepatitis C infection (HCV) occurs in 1% of the world population and can induce several kidney diseases. DM prevalence is increased in individuals with HCV; howev
Externí odkaz:
https://doaj.org/article/f125a7e13ebb469abd38d48f5734a6bb
Autor:
Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer, Stephanie Meyer-Liesener, Natalie Timme, Victor Bardinet, Rocío Chamorro González, Ian C. MacArthur, Celine Y. Chen, Joachim Schulz, Antje M. Wengner, Christian Furth, Birgit Lala, Angelika Eggert, Georg Seifert, Patrick Hundsoerfer, Marieluise Kirchner, Philipp Mertins, Matthias Selbach, Andrej Lissat, Frank Dubois, David Horst, Johannes H. Schulte, Simone Spuler, Daoqi You, Filemon Dela Cruz, Andrew L. Kung, Kerstin Haase, Michela DiVirgilio, Monika Scheer, Michael V. Ortiz, Anton G. Henssen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Alveolar rhabdomyosarcoma is a clinically challenging disease due to the lack of druggable targets. Here the authors show preclinical evidence for ATR inhibitors as a therapeutic option for alveolar rhabdomyosarcoma.
Externí odkaz:
https://doaj.org/article/7544d8ec795c4dae8babbe7a0a303edd
Autor:
Nicole K. Andeen, Vanderlene L. Kung, Josh Robertson, Susan B. Gurley, Rupali S. Avasare, Sneha Sitaraman
Publikováno v:
Glomerular Diseases, Pp 1-12 (2022)
Background: Fibrillary glomerulonephritis (FGN) is found in approximately 1% of native kidney biopsies and was traditionally defined by glomerular deposition of fibrils larger than amyloid (12–24 nm diameter) composed of polyclonal IgG. Recent iden
Externí odkaz:
https://doaj.org/article/94ef4ab5e4af4d258470275268734ed2
Autor:
N. Shukla, M. F. Levine, G. Gundem, D. Domenico, B. Spitzer, N. Bouvier, J. E. Arango-Ossa, D. Glodzik, J. S. Medina-Martínez, U. Bhanot, J. Gutiérrez-Abril, Y. Zhou, E. Fiala, E. Stockfisch, S. Li, M. I. Rodriguez-Sanchez, T. O’Donohue, C. Cobbs, M. H. A. Roehrl, J. Benhamida, F. Iglesias Cardenas, M. Ortiz, M. Kinnaman, S. Roberts, M. Ladanyi, S. Modak, S. Farouk-Sait, E. Slotkin, M. A. Karajannis, F. Dela Cruz, J. Glade Bender, A. Zehir, A. Viale, M. F. Walsh, A. L. Kung, E. Papaemmanuil
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cancer whole-genome and transcriptome sequencing (cWGTS) has been challenging to implement in clinical settings. Here, the authors develop a workflow to deliver robust cWGTS analyses and reports within clinically-relevant timeframes for paediatric, a
Externí odkaz:
https://doaj.org/article/3b93b91639d74dfb8d599ab92c782f7b
Autor:
Nicole K. Andeen, Shahad Abdulameer, Vivek Charu, Jonathan E. Zuckerman, Megan Troxell, Neeraja Kambham, Charles E. Alpers, Behzad Najafian, Roberto F. Nicosia, Kelly D. Smith, Vanderlene L. Kung, Rupali S. Avasare, Anusha Vallurupalli, J. Ashley Jefferson, Douglas Hecox, Leah Swetnam, Michifumi Yamashita, Mercury Lin, Mei Lin Bissonnette, Shreeram Akilesh, Jean Hou
Publikováno v:
Kidney International Reports, Vol 7, Iss 3, Pp 568-579 (2022)
Introduction: There are limited reports on kidney biopsy findings in patients with mantle cell lymphoma (MCL). Methods: We initiated a multi-institutional, retrospective review of kidney biopsy findings in patients with active and treated MCL. Result
Externí odkaz:
https://doaj.org/article/8406b65d010b4e1cbefc568e24d60008
Autor:
Juan S. Medina-Martínez, Juan E. Arango-Ossa, Max F. Levine, Yangyu Zhou, Gunes Gundem, Andrew L. Kung, Elli Papaemmanuil
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background The widespread adoption of high throughput technologies has democratized data generation. However, data processing in accordance with best practices remains challenging and the data capital often becomes siloed. This presents an o
Externí odkaz:
https://doaj.org/article/feb20fb4ac0549128037f4b1ac4084bb
Publikováno v:
Fermentation, Vol 8, Iss 11, p 621 (2022)
We evaluated the effects of a homo-fermentative lactic acid bacteria (homo-LAB) inoculant on the fermentation and microbial communities of alfalfa ensiled at two dry matter (DM) contents of 38 and 46% DM. At both DMs, alfalfa was treated or not with
Externí odkaz:
https://doaj.org/article/54f216727bb147dbb14a7888deea9d33
Autor:
Najeeha T. Iqbal, Sana Syed, Kamran Sadiq, Marium N. Khan, Junaid Iqbal, Jennie Z. Ma, Fayaz Umrani, Sheraz Ahmed, Elizabeth A. Maier, Lee A. Denson, Yael Haberman, Monica M. McNeal, Kenneth D. R. Setchell, Xueheng Zhao, Shahida Qureshi, Lanlan Shen, Christopher A. Moskaluk, Ta-Chiang Liu, Omer Yilmaz, Donald E. Brown, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Sean R. Moore, S. Asad Ali
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Environmental Enteropathy (EE), characterized by alterations in intestinal structure, function, and immune activation, is believed to be an important contributor to childhood undernutrition and its associated morbidities, includin
Externí odkaz:
https://doaj.org/article/0414bfb214f044bf863c410800397858