Donor variation in stored platelets: Higher metabolic rates of platelets are associated with mean platelet volume, activation and donor health

Autor: Ido J. Bontekoe, Pieter F. van der Meer, Bea C. Tanis, Dirk de Korte, Arthur J. Verhoeven, Nicolaas J. H. Raat, Patricia A. C. Specht, Egbert G. Mik, Thomas R. L. Klei

Publikováno v: Transfusion, 62(12), 2609-2620. Wiley-Blackwell
Transfusion, 62(12), 2609-2620. Wiley-Blackwell Publishing Ltd

Background: Platelets (PLTs) differ in glycolytic activity, resulting in rapid acidification of ‘poor’ storing PLT concentrates (PCs) in plasma, or depletion of glucose when stored in PLT additive solution (PAS). We aimed to understand why PLT gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc4cfe5739615df052c2b6be9d78eb3
https://pure.amc.nl/en/publications/donor-variation-in-stored-platelets(373fa33b-9d1e-4c62-aa1a-96bed337ce47).html

Clinical and in vitro evaluation of red blood cells collected and stored in a non-DEHP plasticized bag system

Autor: Christie Vermeulen, Gijs den Besten, Annegeet G. van den Bos, Mya Go, Eric Gouwerok, Richard Vlaar, Martin R. Schipperus, Saskia E. Spelmink, Mart Janssen, Johan W. Lagerberg, Dirk de Korte, Thomas R. L. Klei

Publikováno v: Vox sanguinis, 117(10), 1163-1170. Wiley-Blackwell
Vox Sanguinis, 117, 10, pp. 1163-1170
Vox Sanguinis, 117, 1163-1170

Item does not contain fulltext BACKGROUND AND OBJECTIVES: Di-ethyl-hexyl-phthalate (DEHP) is currently the main plasticizer used for whole blood collection systems. However, in Europe, after May 2025, DEHP may no longer be used above 0.1% (w/w) in me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3554fc79168497b7690c8001d6040d2
https://pubmed.ncbi.nlm.nih.gov/36102116

BLOCKING THE BCL10-MALT1 INTERACTION IN DIFFUSE LARGE B-CELL LYMPHOMA

Autor: L. Maurer, H. Kang, M. Smyers, L. Klei, J. Cheng, M. Trotta, D. Hu, P. Ekambaram, M. Murai, Z. Nikolovska-Coleska, B. Chen, P. Lucas, L. McAllister-Lucas

Publikováno v: Leukemia Research. 121:S23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdb1bafb44a527ed380c50634020a8df
https://doi.org/10.1016/s0145-2126(22)00224-7

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Hemolysis in the spleen drives erythrocyte turnover

Autor: W F J van IJcken, Thomas R. L. Klei, Sietse Q. Nagelkerke, Martijn Veldthuis, Benjamin Nota, R van Zwieten, J Dalimot, Frederik P. J. Mul, F P J van Alphen, T Rademakers, Edwin Oole, Alexander B. Meijer, Mark Hoogenboezem, Taco W. Kuijpers, Søren K. Moestrup, Pia Svendsen, R. van Bruggen

Publikováno v: Klei, T R L, Dalimot, J, Nota, B, Veldthuis, M, Mul, F P J, Rademakers, T, Hoogenboezem, M, Nagelkerke, S Q, van IJcken, W F J, Oole, E, Svendsen, P, Moestrup, S K, van Alphen, F P J, Meijer, A B, Kuijpers, T W, van Zwieten, R & van Bruggen, R 2020, ' Hemolysis in the spleen drives erythrocyte turnover ', Blood, vol. 136, no. 14, pp. 1579-1589 . https://doi.org/10.1182/blood.2020005351
Blood, 136(14), 1579-1589. The American Society of Hematology
Blood, 136(14), 1579. Amer Soc Hematology
Blood, 136(14), 1579-1589. American Society of Hematology

Red pulp macrophages (RPMs) of the spleen mediate turnover of billions of senescent erythrocytes per day. However, the molecular mechanisms involved in sequestration of senescent erythrocytes, their recognition, and their subsequent degradation by RP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35ab5a9fde47f37d72acf4e0a11838b
https://pure.au.dk/portal/da/publications/hemolysis-in-the-spleen-drives-erythrocyte-turnover(507ae87c-abcf-472f-8db3-ed1373f52970).html