Zobrazeno 1 - 10
of 46
pro vyhledávání: '"L Kissner"'
Autor:
Teri L Kissner, Gordon Ruthel, Shahabuddin Alam, Enrique Mann, Dariush Ajami, Mitra Rebek, Eileen Larkin, Stefan Fernandez, Robert G Ulrich, Sun Ping, David S Waugh, Julius Rebek, Kamal U Saikh
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40773 (2012)
Staphylococcal enterotoxin B (SEB) exposure triggers an exaggerated pro-inflammatory cytokine response that often leads to toxic shock syndrome (TSS) associated with organ failure and death. MyD88 mediates pro-inflammatory cytokine signaling induced
Externí odkaz:
https://doaj.org/article/50b5c0b07b3e4f4ea5ee96de78fc9670
Autor:
Teri L Kissner, Gordon Ruthel, Shahabuddin Alam, Robert G Ulrich, Stefan Fernandez, Kamal U Saikh
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15985 (2011)
Ligands binding to Toll-like receptor (TLR), interleukin 1 receptor (IL-1R), or IFN-γR1 are known to trigger MyD88-mediated signaling, which activates pro-inflammatory cytokine responses. Recently we reported that staphylococcal enterotoxins (SEA or
Externí odkaz:
https://doaj.org/article/8baea8e7d62248f19ac86678eb572f62
Autor:
Martha Hale, Dariush Ajami, Melissa Degardin, Daniel Angus Ryan, Mitra Rebek, Michael D. Cameron, Julius Rebek, Kamal U. Saikh, Shahabuddin Alam, Teri L. Kissner
Publikováno v:
Chemical biologydrug design. 90(6)
Small molecules were developed to attenuate proinflammatory cytokines resulting from activation of MyD88-mediated toll-like receptor (TLR) signaling by Francisella tularensis. Fifty-three tripeptide derivatives were synthesized to mimic a key BB-loop
Autor:
Mark A. Olson, David S. Waugh, Teri L. Kissner, Michael S. Lee, Kamal U. Saikh, Shahabuddin Alam
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-2 (2018)
A correction has been published and is appended to both the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Autor:
K Rosenthal, B. Bestvater, J. R. Pullankavumkal, M. Mangler, L. Kissner, Alexander Weichert, M. Lanowska
Publikováno v:
Der Gynäkologe. 48:399-401
Publikováno v:
Immunology. 130:516-526
Staphylococcal enterotoxin (SE) -induced toxic shock is triggered by inflammatory cytokine signal amplification after SE binding to major histocompatibility complex class II molecules on antigen-presenting cells and T-cell receptors. Identifying host
Autor:
David S. Waugh, Mark A. Olson, Teri L. Kissner, Shahabuddin Alam, Michael S. Lee, Kamal U. Saikh
Publikováno v:
Scientific Reports
In this study, we used high-throughput computational screening to discover drug-like inhibitors of the host MyD88 protein-protein signaling interaction implicated in the potentially lethal immune response associated with Staphylococcal enterotoxins.
Autor:
Kamal U Saikh, David S. Waugh, Robert G. Ulrich, Beverly Dyas, Teri L. Kissner, Joseph E. Tropea
Publikováno v:
The Journal of Infectious Diseases. 194:1753-1760
Cell contact by the plague bacterium Yersinia pestis initiates the injection of several virulence factors that target biochemical pathways critical for host clearance of bacteria. Despite this impairment of innate immunity, it is unclear whether anti
Publikováno v:
The Journal of Infectious Diseases. 188:1562-1570
Using the natural killer (NK) cell-surface marker CD56 to study NK T cells in peripheral blood, we found that their frequency in mononuclear cells among healthy individuals was 1%-20% (average, 7.3%) and sporadically increased 4-5-fold within individ
Publikováno v:
Clinical and Vaccine Immunology. 10:1065-1073
Natural killer T (NKT) cells, coexpressing natural killer (NK) and T-cell receptors (TCR), are associated with immunity to viruses, tumors, and parasites. A well-characterized subclass of these NKT cells expresses biased TCR and recognizes glycolipid