Zobrazeno 1 - 10
of 26
pro vyhledávání: '"L K Jennings"'
Publikováno v:
European Heart Journal. 42
Introduction The activated partial thromboplastin time (aPTT) assay is a test routinely used to evaluate abnormalities or deficiencies in coagulation factors of the intrinsic and common pathways. The composition of the surface activator and phospholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad4d21467f22fa5ab14b5f353e06934
https://doi.org/10.1093/eurheartj/ehab724.2976
https://doi.org/10.1093/eurheartj/ehab724.2976
Publikováno v:
Water Research. 35:3448-3456
The inhibition of light emitted by the bioluminescent bacterium, Vibrio fischeri, is the basis for several toxicity bioassays. The inhibitory effects of 81 chemicals, after 5 min contact time, were studied at eight concentrations using reagents from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c1694e71b59cf27d6d4dfb9627ebbc
https://doi.org/10.1016/s0043-1354(01)00067-7
https://doi.org/10.1016/s0043-1354(01)00067-7
Publikováno v:
The Histochemical Journal. 29:153-165
CD9 is a 24-kDa membrane glycoprotein expressed on the surface of human platelets and potentially involved in cellular activation and adhesion functions. This protein belongs to a recently delineated family of cell-surface antigens that span the memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1abc1ee3dd01b928e9ead1003b116429
https://doi.org/10.1023/a:1026437522882
https://doi.org/10.1023/a:1026437522882
Autor:
W C, Kouns, P J, Newman, K J, Puckett, A A, Miller, C D, Wall, C F, Fox, J M, Seyer, L K, Jennings
Publikováno v:
Blood. 78:3215-3223
Glycoprotein (GP) IIb-IIIa serves as the platelet fibrinogen receptor. Studies of the tertiary structure of GPIIIa have shown that the protein has a large loop structure of at least 325 amino acids in length. To further characterize this loop structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e10f6c53e6b1a74888c0f76c290bf6
https://doi.org/10.1182/blood.v78.12.3215.3215
https://doi.org/10.1182/blood.v78.12.3215.3215
Publikováno v:
Thrombosis and haemostasis. 84(6)
The glycoprotein (GP) IIb-IIIa complex is an attractive anti-platelet target for the prevention of thrombotic events associated with coronary artery disease. Although GPIIb-IIIa antagonists inhibit GPIIb-IIIa binding to its ligands, the interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21a24cb5f35f73b8287156edae52052e
https://pubmed.ncbi.nlm.nih.gov/11154119
https://pubmed.ncbi.nlm.nih.gov/11154119
Publikováno v:
Blood. 96(7)
Glycoprotein (GP) IIb-IIIa plays a critical role in platelet aggregation and platelet-mediated clot retraction. This study examined the intramolecular relationship between GPIIb-IIIa activation and fibrinogen binding, platelet aggregation, and platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baecf42a026d5002ae60c4bc63b23ad8
https://pubmed.ncbi.nlm.nih.gov/11001901
https://pubmed.ncbi.nlm.nih.gov/11001901
Publikováno v:
Thrombosis and haemostasis. 80(1)
Platelets from Glanzmann thrombasthenia patient BL express approximately 30% of the normal alphaIIbbeta3 content and support fibrin-mediated clot retraction, but fail to bind fibrinogen or aggregate following cellular activation. BL platelets bind ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03cabe5d70ba0d101ec35aebf71234ec
https://pubmed.ncbi.nlm.nih.gov/9684783
https://pubmed.ncbi.nlm.nih.gov/9684783
Publikováno v:
Blood. 88(10)
Ligand-induced binding sites (LIBS) are neoantigenic regions of glycoprotein (GP)IIb-IIIa that are exposed upon interaction of the receptor with the ligand fibrinogen or the ligand recognition sequence (RGDS). LIBS have been suggested to contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a19fa810944c6ecda9d170b92dee48f5
https://pubmed.ncbi.nlm.nih.gov/8916946
https://pubmed.ncbi.nlm.nih.gov/8916946
Publikováno v:
Thrombosis and haemostasis. 74(6)
We examined interspecies differences in the function of the platelet fibrinogen receptor, GPIIb-IIIa, by comparing platelet aggregation responses to adenosine diphosphate (ADP) added alone or in combination with a GPIIIa specific monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::679cb06ff10a0de1b9567972333de175
https://pubmed.ncbi.nlm.nih.gov/8772236
https://pubmed.ncbi.nlm.nih.gov/8772236
Autor:
W C, Kouns, D, Kirchhofer, P, Hadváry, A, Edenhofer, T, Weller, G, Pfenninger, H R, Baumgartner, L K, Jennings, B, Steiner
Publikováno v:
Blood. 80(10)
Platelet glycoprotein (GP) IIb-IIIa inhibitors may become useful antithrombotic agents. Ro 43-5054 is a low molecular weight, noncyclic, peptidomimetic inhibitor that is three orders of magnitude more potent than RGDS in inhibiting fibrinogen binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64f57b1b3d910aa326d67799884a0198
https://pubmed.ncbi.nlm.nih.gov/1384788
https://pubmed.ncbi.nlm.nih.gov/1384788