Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L K, Klaidman"'
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 2:125-134
Nicotinamide can facilitate DNA repair by inhibiting poly(ADP-ribose) polymerase, increasing NAD levels and adjusting other related enzyme activities. This review will summarize recent work on the design of poly(ADP-ribose) polymerase inhibitors, pol
Publikováno v:
Redox Report. 3:273-279
A new mechanism of oxygen radical formation in dopaminergic neurons is proposed, based on the oxidative mechanism of tyrosine hydroxylase. The cofactor (6R,6S)-5,6,7,8-tetrahydrobiopterin can rearrange in solution which allows an autoxidation reactio
Publikováno v:
Journal of medicine. 24(6)
Human immunodeficiency virus (HIV) infection is associated with altered levels of glutathione (GSH) in cells and extracellular fluids. GSH is essential for lymphocyte proliferation and inhibits HIV replication. Therefore, determination of GSH and glu