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An evaluation of the proposed OECD testing strategy for skin corrosion

Autor: A P, Worth, J H, Fentem, M, Balls, P A, Botham, R D, Curren, L K, Earl, D J, Esdaile

Publikováno v: Alternatives to laboratory animals : ATLA. 26(5)

The use of testing strategies which incorporate a range of alternative methods and which use animals only as a last resort is widely considered to provide a reliable way of predicting chemical toxicity while minimising animal testing. The widespread

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::89c13fef7363f2453b3c2de6db167ae2
https://pubmed.ncbi.nlm.nih.gov/26042494

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Alternative methods for skin irritation testing: the current status

Autor: P A, Botham, L K, Earl, J H, Fentem, R, Roguet, J J, van de Sandt

Publikováno v: Alternatives to laboratory animals : ATLA. 26(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::148fc9b1ffbb2b3f5a900687339fee6f
https://pubmed.ncbi.nlm.nih.gov/26043398

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Report on the COLIPA Workshop on Mechanisms of Eye Irritation

Autor: L H, Bruner, O, de Silva, L K, Earl, D L, Easty, W, Pape, H, Spielmann

Publikováno v: Alternatives to laboratory animals : ATLA. 26(6)

This report summarises the discussions of a workshop sponsored by the European Cosmetics, Toiletries and Perfumery Association (COLIPA). The workshop discussed the state-of-the-art of eye irritancy testing, and made recommendations as to the best way

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4534a458882ff2e18eea8b18c54b4c78
https://pubmed.ncbi.nlm.nih.gov/26042583

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Eye Irritation Testing: The Way Forward. The Report and Recommendations of ECVAM Workshop 34

Autor: M, Balls, N, Berg, L H, Bruner, R D, Curren, O, de Silva, L K, Earl, D J, Esdaile, J H, Fentem, M, Liebsch, Y, Ohno, M K, Prinsen, H, Spielmann, A P, Worth

Publikováno v: Alternatives to laboratory animals : ATLA. 27(1)

This is the report of the thirty-fourth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM's main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scienti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d88eb6c242e1d742cfb602e4ed28a912
https://pubmed.ncbi.nlm.nih.gov/25423402

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A strategy for the assessment of skin corrosion and irritation without animal testing / Strategie zu Bewertung von Hautschäden und -irritationen ohne Tierversuche

Autor: D. A. Basketter, M.D. Barratt, M. Chamberlain, E. Whittle, L. K. Earl

Publikováno v: Tenside Surfactants Detergents. 34:446-449

The approach developed by the authors for the assessment of skin irritation makes maximum use of existing information on similar structures or formulations and incorporates a stepwise strategy to determine firstly, the corrosive potential of a substa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c55a40dd9f97b5b2ed1985a318611b35
https://doi.org/10.1515/tsd-1997-340617

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The absorption, distribution and excretion of 1- and 2

Autor: D J, Sanders, D, Howes, L K, Earl

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 39(7)

Human breast milk is rich in 2-palmitoyl 1,3 unsaturated triacyglycerols and during the neonatal period, when milk is the sole source of nutrients, their role could be particularly important. Betapol is a novel triacylglycerol mix resembling human br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72c175d6b6e1aa5aedf4db98843f2f2c
https://pubmed.ncbi.nlm.nih.gov/11397517

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