Zobrazeno 1 - 10
of 82
pro vyhledávání: '"L K, Curtiss"'
Autor:
M L Phillips, C Pullinger, I Kroes, J Kroes, D A Hardman, G Chen, L K Curtiss, M M Gutierrez, J P Kane, V N Schumaker
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 6, Pp 1170-1177 (1997)
Individuals homozygous for the e2 allele encoding apolipoprotein E exhibit a remnant removal defect and accumulate substantial levels of intestinally derived particles containing apolipoprotein B-48 (apoB-48). Such lipoproteins were isolated from the
Externí odkaz:
https://doaj.org/article/cd13740707514b51b0b6f7cb555b7a39
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 3, Pp 516-525 (1997)
The interaction of lipopolysaccharide binding protein (LBP) with apolipoprotein (apo)A-I on high density lipoproteins (HDL) was studied in solid phase ligand binding assays with a biotinylated LBP-specific antibody. The association was dependent on L
Externí odkaz:
https://doaj.org/article/25b294e93b9845a1894b8693b6438d83
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 1, Pp 77-85 (1997)
We have shown previously that the activity of lipoprotein lipase (LPL), the major enzyme responsible for hydrolysis of triglyceride contained in circulating lipoproteins, is associated with lipoproteins in postheparin plasma. In other studies, microt
Externí odkaz:
https://doaj.org/article/611bf2262e4e4b62b5f80dba8d488555
Autor:
L K Curtiss, C L Banka
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 4, Pp 884-892 (1996)
A direct approach is described for generating human apolipoprotein (apo) A-I-specific monoclonal antibodies with defined linear epitopes. The antibodies have comparable binding affinity for delipidated apoA-I and apoA-I on high density lipoproteins (
Externí odkaz:
https://doaj.org/article/9b558f2e571c4835ab6d68627e3cc4f0
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 6, Pp 1309-1315 (1996)
Abetalipoproteinemia (ABL) is an autosomal recessive disease characterized by the inability of the liver and intestine to secrete apolipoprotein B (apoB). Mutations in the microsomal triglyceride transfer protein (MTP) gene, but not the apoB gene, ar
Externí odkaz:
https://doaj.org/article/3441ac540ba54b6386a0efaa0137f81f
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 9, Pp 2027-2037 (1995)
In the present study, the relative positions of 11 anti-apolipoprotein B monoclonal antibodies have been mapped onto the surface of human low density lipoproteins by electron microscopy. As the epitopes recognized by these antibodies have been previo
Externí odkaz:
https://doaj.org/article/564ac34f0a3b4d64867b92d44aa5443e
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 5, Pp 1058-1065 (1995)
Normal high density lipoprotein (N-HDL) is remodeled during acute phase (AP) reactions by the association of serum amyloid A (SAA) and the depletion of apolipoprotein (apo) A-I. To determine the impact of this remodeling on HDL function, the capaciti
Externí odkaz:
https://doaj.org/article/e3d24020503749678c2e5a129c25d82f
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 1, Pp 80-88 (1995)
Apolipoprotein (apo) E, via its receptor binding domain contained in residues 140-150, mediates hepatic and peripheral tissue binding of cholesterol-rich lipoproteins. Previously, we reported that a synthetic peptide representing a linear tandem repe
Externí odkaz:
https://doaj.org/article/637f113f77334e99adfcbaf9fc0c541e
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 8, Pp 1469-1476 (1994)
Familial defective apolipoprotein B-100 (FDB) is a genetic disorder apparently caused by a single amino acid substitution (Arg3500–>Gln) that disrupts the binding of low density lipoproteins (LDL) to the LDL receptor. The plasma of FDB heterozygote
Externí odkaz:
https://doaj.org/article/b80692fa64d2496c8a5b1a82a01aefe9
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 3, Pp 491-500 (1994)
In a previous study we demonstrated that isocaloric substitution of fish oil (FO) for lard in the diet of cynomolgus monkeys resulted in low density lipoproteins (LDL) that were poorer competitors for binding of a standard 125I-labeled LDL and led to
Externí odkaz:
https://doaj.org/article/d4dc8162ddcc447ca6312a48c977b8fe