Zobrazeno 1 - 10
of 202
pro vyhledávání: '"L K, Borysiewicz"'
Publikováno v:
Journal of Immunological Methods. 221:1-16
HLA class I transgenic mice are a powerful research tool which have been used as models for human immune responses. This review describes the generation of the different HLA class I transgenic mice, the techniques used to improve expression of the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd4c68376154a60d0ede9a6cd910551
https://doi.org/10.1016/s0022-1759(98)00162-8
https://doi.org/10.1016/s0022-1759(98)00162-8
Autor:
E.A. Rollinson, Alan James Munro, Julian Hickling, K. Vousden, E. Rutherford, Mike Boursnell, N. Rolley, L. K. Borysiewicz, Stephen Charles Inglis, C. S. Mclean
Publikováno v:
Vaccine
The presence and consistent expression of the genes encoding the human papillomavirus (HPV) E6 and E7 proteins in the great majority of cervical tumours presents the opportunity for an immunotherapeutic approach for control of the disease. This repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d1ba7a10cb2bcc3a149784086fac64
https://doi.org/10.1016/s0264-410x(96)00117-x
https://doi.org/10.1016/s0264-410x(96)00117-x
Autor:
D. Gheysen, A. S. Evans, Alison Nina Fiander, M. Delchambre, L. K. Borysiewicz, J. I. Hopkins
Publikováno v:
Journal of Medical Virology. 49:124-131
Human cytomegalovirus (HCMV) is associated with significant morbidity and mortality following immunosuppression and in pregnancy. HCMV infection may be accompanied by acute disease but persists asymptomatically. Cytotoxic T lymphocytes (CTL) appear t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77405be52ddf121d22548a221e860d0a
https://doi.org/10.1002/(sici)1096-9071(199606)49:2<124::aid-jmv9>3.0.co
https://doi.org/10.1002/(sici)1096-9071(199606)49:2<124::aid-jmv9>3.0.co
Publikováno v:
The Journal of Immunology. 155:5046-5056
CD8+CD57+ lymphocytes from normal peripheral blood are divided into T cells expressing high levels of CD8 and NK cells expressing low levels of surface CD8. Increased numbers of CD8highCD57+ T cells correlate with previous exposure to human cytomegal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc82ac3f92cdb66a5df63e9cd542d4c
https://doi.org/10.4049/jimmunol.155.10.5046
https://doi.org/10.4049/jimmunol.155.10.5046
Publikováno v:
Journal of General Virology. 75:3319-3325
Human cytomegalovirus (HCMV) causes a c.p.e. characterized by rounding of the infected cell. Since interactions with the extracellular matrix may be involved in the cell rounding, we have analysed the expression of integrins, which are the main cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205d97108bd775a4b158d385e50dd9ca
https://doi.org/10.1099/0022-1317-75-12-3319
https://doi.org/10.1099/0022-1317-75-12-3319
Autor:
H. P. Lambert, L. C. Archard, L. K. Borysiewicz, A. David, R. H. Edwards, Michael Sharpe, Keith Hawton, R. J. Lane, A. W. Clare, J. E. Banatvala
Publikováno v:
Journal of the Royal Society of Medicine. 84:118-121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4daeb48312794dd88ffa92ad22aa871
https://doi.org/10.1177/014107689108400224
https://doi.org/10.1177/014107689108400224
Autor:
Alison Nina Fiander, Mererid Evans, K. L. Smith, Sarah Jane Youde, K. J. Thomas, L. K. Borysiewicz, Stephen Man
Publikováno v:
International journal of cancer. 122(12)
Persistent human papillomavirus type 16 (HPV16) infection is associated with the development of more than 50% of cervical cancers. The HPV16 E6 and E7 oncoproteins are constitutively expressed in cervical carcinomas and are attractive targets for cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c297dba38580ca2b894f43e2c667517b
https://pubmed.ncbi.nlm.nih.gov/18366058
https://pubmed.ncbi.nlm.nih.gov/18366058
Publikováno v:
European Journal of Immunology. 20:271-275
We have tested the potential role of thyroid cell intercellular adhesion molecule-1 (ICAM-1) expression by in vitro assays of cell clustering and cytotoxicity. Increased ICAM-1 appeared within 24 h of thyroid cell stimulation with cytokines and was n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68d5eeeb3b69f3b084af88e36a5199f
https://doi.org/10.1002/eji.1830200207
https://doi.org/10.1002/eji.1830200207
Autor:
L. K. Borysiewicz, Bharat Jasani, Malcolm Adams, Malcolm David Mason, A. S. Evans, Hossein Navabi, Stephen Man, Alison Nina Fiander
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461351948
Cervical cancer is the second most common cause of cancer death world wide’ and is a particular problem in developing countries. Even with optimum treatment approximately 40% continue to die from this disease.2There is therefore a need for new stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4add0840738054de689f2f064579dc49
https://doi.org/10.1007/978-1-4615-0685-0_61
https://doi.org/10.1007/978-1-4615-0685-0_61
Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia
Autor:
H J, Bontkes, T D, de Gruijl, A J, van den Muysenberg, R H, Verheijen, M J, Stukart, C J, Meijer, R J, Scheper, S N, Stacey, M F, Duggan-Keen, P L, Stern, S, Man, L K, Borysiewicz, J M, Walboomers
Publikováno v:
International journal of cancer. 88(1)
Infection with oncogenic human papillomavirus (HPV) types is associated with the development of cervical neoplasia (CIN). The E6 and E7 oncoproteins are constitutively expressed in these lesions and are therefore putative targets for the immune respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5f10c28b6b5266368474dfc8b186cc6
https://pubmed.ncbi.nlm.nih.gov/10962445
https://pubmed.ncbi.nlm.nih.gov/10962445