Predicting mortality in febrile adults: comparative performance of the MEWS, qSOFA, and UVA scores using prospectively collected data among patients in four health-care sites in sub-Saharan Africa and South-Eastern AsiaResearch in context

Autor: Sham Lal, Manophab Luangraj, Suzanne H. Keddie, Elizabeth A. Ashley, Oliver Baerenbold, Quique Bassat, John Bradley, John A. Crump, Nicholas A. Feasey, Edward W. Green, Kevin C. Kain, Ioana D. Olaru, David G. Lalloo, Chrissy h. Roberts, David C.W. Mabey, Christopher C. Moore, Heidi Hopkins, Sara Ajanovic, Benjamin Amos, Stéphanie Baghoumina, Núria Balanza, Tsitsi Bandason, Tapan Bhattacharyya, Stuart D. Blacksell, Zumilda Boca, Christian Bottomley, Justina M. Bramugy, Clare IR. Chandler, Vilada Chansamouth, Mabvuto Chimenya, Joseph Chipanga, Anelsio Cossa, Ethel Dauya, Catherine Davis, Xavier de Lamballerie, Justin Dixon, Somyoth Douangphachanh, Audrey Dubot-Pérès, Michelle M. Durkin, Rashida A. Ferrand, Colin Fink, Elizabeth JA. Fitchett, Alessandro Gerada, Stephen R. Graves, Edward Green, Becca L. Handley, Coll D. Hutchison, Risara Jaksuwan, Jessica Jervis, Jayne Jones, Khamxeng Khounpaseuth, Katharina Kranzer, Khamfong Kunlaya, Pankaj Lal, Yoel Lubell, David CW. Mabey, Eleanor MacPherson, Forget Makoga, Sengchanh Manichan, Tegwen Marlais, Florian Maurer, Mayfong Mayxay, Michael Miles, Polycarp Mogeni, Campos Mucasse, Paul N. Newton, Chelsea Nguyen, Vilayouth Phimolsarnnousith, Mathieu Picardeau, Chrissy H. Roberts, Amphone Sengduangphachanh, Siho Sengsavang, Molly Sibanda, Somvai Singha, John Stenos, Ampai Tanganuchitcharnchai, Hira Tanvir, James E. Ussher, Marta Valente, Marie A. Voice, Manivanh Vongsouvath, Msopole Wamaka, L Joseph Wheat, Shunmay Yeung

Publikováno v: EClinicalMedicine, Vol 77, Iss , Pp 102856- (2024)

Summary: Background: Clinical severity scores can identify patients at risk of severe disease and death, and improve patient management. The modified early warning score (MEWS), the quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA),

Externí odkaz: https://doaj.org/article/472ab60c07af4c819f058bc83c88007e

Evaluation of an enzyme immunoassay and immunodiffusion for detection of anti‐Histoplasma antibodies in serum from cats and dogs

Autor: Rebecca Tims, Andrew S. Hanzlicek, Laura Nafe, Michelle M. Durkin, Jennifer Smith‐Davis, L. Joseph Wheat

Publikováno v: Journal of Veterinary Internal Medicine, Vol 37, Iss 3, Pp 1007-1014 (2023)

Abstract Background Histoplasma antigen and anti‐Histoplasma antibody detection are used to support the diagnosis of histoplasmosis. There is a paucity of published data on antibody assays. Objectives Our primary hypothesis was that anti‐Histopla

Externí odkaz: https://doaj.org/article/d2ee80b26a9b4691bfab94dbc754b57f

Invasive fungal rhinitis with adnexal involvement caused by in a cat from a non-enzootic location

Autor: Catherine R Grinstead, Andrew S Hanzlicek, Heather W Largura, L Joseph Wheat

Publikováno v: Journal of Feline Medicine and Surgery Open Reports, Vol 7 (2021)

Case summary This report describes a cat with a rare form of histoplasmosis: invasive rhinitis with adnexal involvement, mimicking disease more commonly caused by cryptococcosis or aspergillosis. This case is especially noteworthy as it was from an a

Externí odkaz: https://doaj.org/article/35b32309a259497fbe205d87450fc745

Characterization of an Uncinocarpus reesii-expressed recombinant tube precipitin antigen of Coccidioides posadasii for serodiagnosis.

Autor: Jieh-Juen Yu, Eric Holbrook, Yu-Rou Liao, Robert Zarnowski, David R Andes, L Joseph Wheat, Joshua Malo, Chiung-Yu Hung

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0221228 (2019)

Early and accurate diagnosis of coccidioidomycosis, also known as Valley fever, is critical for appropriate disease treatment and management. Current serodiagnosis is based on the detection of patient serum antibodies that react with tube precipitin

Externí odkaz: https://doaj.org/article/f9483fd3f95d4fafa90934295887ffcd

Central Nervous System Infection with Histoplasma capsulatum

Autor: James Riddell, L. Joseph Wheat

Publikováno v: Journal of Fungi, Vol 5, Iss 3, p 70 (2019)

Histoplasmosis is an endemic fungal infection that may affect both immune compromised and non-immune compromised individuals. It is now recognized that the geographic range of this organism is larger than previously understood, placing more people at

Externí odkaz: https://doaj.org/article/277e030462834664b4c6318c74925ba9