Zobrazeno 1 - 10
of 19
pro vyhledávání: '"L James Frye"'
Autor:
Maral Budak, Joseph M Cicchese, Pauline Maiello, H Jacob Borish, Alexander G White, Harris B Chishti, Jaime Tomko, L James Frye, Daniel Fillmore, Kara Kracinovsky, Jennifer Sakal, Charles A Scanga, Philana Ling Lin, Véronique Dartois, Jennifer J Linderman, JoAnne L Flynn, Denise E Kirschner
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1010823 (2023)
Tuberculosis (TB) continues to be one of the deadliest infectious diseases in the world, causing ~1.5 million deaths every year. The World Health Organization initiated an End TB Strategy that aims to reduce TB-related deaths in 2035 by 95%. Recent r
Externí odkaz:
https://doaj.org/article/6c3730d6ea76411e8f9be1bff53e7a93
Autor:
Amy L Hartman, Sham Nambulli, Cynthia M McMillen, Alexander G White, Natasha Louise Tilston-Lunel, Joseph R Albe, Emily Cottle, Matthew D Dunn, L James Frye, Theron H Gilliland, Emily L Olsen, Katherine J O'Malley, Madeline M Schwarz, Jaime A Tomko, Reagan C Walker, Mengying Xia, Matthew S Hartman, Edwin Klein, Charles A Scanga, JoAnne L Flynn, William B Klimstra, Anita K McElroy, Douglas S Reed, W Paul Duprex
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008903 (2020)
Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (A
Externí odkaz:
https://doaj.org/article/9af9b959abac4308b999b6e2d34961ea
Autor:
Philana Ling Lin, Pauline Maiello, Hannah P Gideon, M Teresa Coleman, Anthony M Cadena, Mark A Rodgers, Robert Gregg, Melanie O'Malley, Jaime Tomko, Daniel Fillmore, L James Frye, Tara Rutledge, Robert M DiFazio, Christopher Janssen, Edwin Klein, Peter L Andersen, Sarah M Fortune, JoAnne L Flynn
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005739 (2016)
Mycobacterium tuberculosis infection presents across a spectrum in humans, from latent infection to active tuberculosis. Among those with latent tuberculosis, it is now recognized that there is also a spectrum of infection and this likely contributes
Externí odkaz:
https://doaj.org/article/618e2e8d7ad5407fae0a0f8a69153c72
Autor:
Nicole L. Grant, Pauline Maiello, Edwin Klein, Philana Ling Lin, H. Jacob Borish, Jaime Tomko, L. James Frye, Alexander G. White, Denise E. Kirschner, Joshua T. Mattila, JoAnne L. Flynn
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110826- (2022)
Summary: Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a global health concern, yearly resulting in 10 million new cases of active TB. Immunologic investigation of lung granulomas is essential for understanding host c
Externí odkaz:
https://doaj.org/article/27d79ee8867c4472a720d0e7466b5302
Autor:
Jessica Marie Medrano, Pauline Maiello, Tara Rutledge, Jaime Tomko, Mark A Rodgers, Daniel Fillmore, L James Frye, Christopher Janssen, Edwin Klein, JoAnne L Flynn, Philana Ling Lin
Publikováno v:
The Journal of Infectious Diseases. 227:592-601
Mycobacterium tuberculosis infection outcomes have been described as active tuberculosis or latent infection but a spectrum of outcomes is now recognized. We used a nonhuman primate model, which recapitulates human infection, to characterize the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13abb0590dd7947be43319eddfcd76b
https://doi.org/10.1093/infdis/jiac504
https://doi.org/10.1093/infdis/jiac504
Autor:
R.M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sampling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a42fa0baad62a328a1b992d88f506f
https://doi.org/10.1101/2023.04.03.535218
https://doi.org/10.1101/2023.04.03.535218
Autor:
Maral Budak, Joseph M. Cicchese, Pauline Maiello, H. Jacob Borish, Alexander G. White, Harris B. Chishti, Jaime Tomko, L. James Frye, Daniel Fillmore, Kara Kracinovsky, Jennifer Sakal, Charles A. Scanga, Philana Ling Lin, Véronique Dartois, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner
Tuberculosis (TB) continues to be one of the deadliest infectious diseases in the world, causing ~1.5 million deaths every year. The World Health Organization initiated anEnd TB Strategythat aims to reduce TB-related deaths in 2035 by 95%. Recent res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4db79801993e621900472ac13341a2ff
https://doi.org/10.1101/2022.12.18.520959
https://doi.org/10.1101/2022.12.18.520959
Autor:
Jessica Marie, Medrano, Pauline, Maiello, Tara, Rutledge, Jaime, Tomko, Mark A, Rodgers, Daniel, Fillmore, L James, Frye, Christopher, Janssen, Edwin, Klein, JoAnne L, Flynn, Philana Ling, Lin
Publikováno v:
The Journal of infectious diseases.
Mycobacterium tuberculosis (Mtb) infection outcomes have been described as active tuberculosis (TB) or latent infection but a spectrum of outcomes is now recognized. We used a non-human primate model which recapitulates human infection to characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::999a217d281897b6a6fc7aeb5abfb538
https://pubmed.ncbi.nlm.nih.gov/36611221
https://pubmed.ncbi.nlm.nih.gov/36611221
Autor:
Nicole L. Grant, Pauline Maiello, Edwin Klein, Philana Ling Lin, H. Jacob Borish, Jaime Tomko, L. James Frye, Alexander G. White, Denise E. Kirschner, Joshua T. Mattila, JoAnne L. Flynn
SUMMARYMycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a global health concern, yearly resulting in 10 million new cases of active TB. Immunologic investigation of lung granulomas is essential for understanding host con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff54b069c7bcba7db81354228a5d2c7
https://doi.org/10.1101/2022.01.25.477732
https://doi.org/10.1101/2022.01.25.477732
Autor:
Patricia A. Darrah, Joseph J. Zeppa, Chuangqi Wang, Edward B. Irvine, Allison N. Bucsan, Mark A. Rodgers, Supriya Pokkali, Joshua A. Hackney, Megha Kamath, Alexander G. White, H. Jacob Borish, L. James Frye, Jaime Tomko, Kara Kracinovsky, Philana L. Lin, Edwin Klein, Charles A. Scanga, Galit Alter, Sarah M. Fortune, Douglas A. Lauffenburger, JoAnne L. Flynn, Robert A. Seder, Pauline Maiello, Mario Roederer
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de52afa6e0b26e939cf7a9f1de639fa7
https://doi.org/10.2139/ssrn.4276248
https://doi.org/10.2139/ssrn.4276248