Zobrazeno 1 - 10
of 36
pro vyhledávání: '"L Jackson Roberts II"'
Autor:
Christi T Salisbury-Ruf, Clinton C Bertram, Aurelia Vergeade, Daniel S Lark, Qiong Shi, Marlene L Heberling, Niki L Fortune, G Donald Okoye, W Gray Jerome, Quinn S Wells, Josh Fessel, Javid Moslehi, Heidi Chen, L Jackson Roberts II, Olivier Boutaud, Eric R Gamazon, Sandra S Zinkel
Publikováno v:
eLife, Vol 7 (2018)
Bcl-2 family proteins reorganize mitochondrial membranes during apoptosis, to form pores and rearrange cristae. In vitro and in vivo analysis integrated with human genetics reveals a novel homeostatic mitochondrial function for Bcl-2 family protein B
Externí odkaz:
https://doaj.org/article/713e95df63974051b6c65861bd7d12a1
Publikováno v:
Neurobiology of Disease, Vol 98, Iss , Pp 88-99 (2017)
Cognitive dysfunction is a major comorbidity of the epilepsies; however, treatments targeting seizure-associated cognitive dysfunction, particularly deficits in learning and memory are not available. Isoketals and neuroketals, collectively known as g
Externí odkaz:
https://doaj.org/article/7b7809f333204bfe9153813bebc72318
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 7, Pp 1972-1979 (2013)
Despite animal and in vitro studies demonstrating pro-oxidative effects of Hg, previous human work showed no relationship between tissue Hg and plasma levels of F2-isoprostanes (IsoPs), a whole-body oxidative stress marker. We hypothesized that anoth
Externí odkaz:
https://doaj.org/article/fd449cd314c340a084307ab7a21b5eb5
Autor:
C. Blake Sullivan, Elena Matafonova, L. Jackson Roberts, II, Venkataraman Amarnath, Sean S. Davies
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 5, Pp 999-1009 (2010)
Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are γ-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions
Externí odkaz:
https://doaj.org/article/2734229a4cd34f52a4bd8558ff93b624
Autor:
Gopal K. Marathe, Kathleen A. Harrison, L. Jackson Roberts, II, Jason D. Morrow, Robert C. Murphy, Larry W. Tjoelker, Stephen M. Prescott, Guy A. Zimmerman, Thomas M. McIntyre
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 587-596 (2001)
Unmitigated oxidative stress is deleterious, as epitomized by CCl4 intoxication. In this well-characterized model of free radical-initiated damage, liver metabolism of CCl4 to CCl3. causes lipid peroxidation, F-ring isoprostane formation, and patholo
Externí odkaz:
https://doaj.org/article/782ebb3db6c541f2b370e6269796dade
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 8, Pp 1589-1593 (1998)
D2/E2-isoprostanes are prostaglandin D2/E2-like compounds that are produced in vivo as non-enzymatic products of free radical catalyzed peroxidation of arachidonic acid. One E2-isoprostane that should be formed is 15-E2t-isoprostane (8-iso-prostaglan
Externí odkaz:
https://doaj.org/article/b912a7fbd7ca4a1da42b22b647991bca
Publikováno v:
Journal of Lipid Research, Vol 50, Iss , Pp S219-S223 (2009)
The isoprostanes (IsoPs) are a unique series of prostaglandin-like compounds formed in vivo via a nonenzymatic mechanism involving the free radical-initiated peroxidation of arachidonic acid. This article summarizes our current knowledge of these com
Externí odkaz:
https://doaj.org/article/d2fad04cad13485e86b644b2d9a62df4
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