Zobrazeno 1 - 9
of 9
pro vyhledávání: '"L J Lees"'
Publikováno v:
European Journal of Clinical Microbiology. 2:340-344
Eight volunteers each received lg of probenecid followed immediately by 1.5 g sultamicillin, both given by the oral route. Plasma concentrations of ampicillin and sulbactam were measured using a differential bioassay method. An ampicillin mean peak p
Publikováno v:
British Journal of Clinical Pharmacology. 27:851-859
1. Azole antifungal agents such as ketoconazole act by inhibiting cytochrome P-450 mediated sterol synthesis in the fungal cell membrane and thus have the potential to interfere with mammalian steroidogenesis. Fluconazole is a novel orally-effective
Publikováno v:
British Journal of Clinical Pharmacology. 14:213-217
1 Plasma and biliary concentrations of amoxycillin and ceftriaxone were measured after bolus intravenous administration (500 mg) in four subjects with normal hepato-biliary and renal function. 2 The mean plasma elimination half-life for ceftriaxone (
Publikováno v:
Journal of Infectious Diseases. 137:82-86
A double-stranded RNA of fungal origin (BRL 5907) was given intranasally to volunteers. Apart from mild local irritancy of the higher dosage, the compound was well tolerated. A double-blind placebo-controlled trial of a three-day course (5 mg per day
Autor:
L J, Lees, J W, Harding
Publikováno v:
The British journal of clinical practice. 28(10)
Publikováno v:
Chemotherapy. 24(4)
Talampicillin is an ester of ampicillin which is readily hydrolysed on absorption to release ampicillin. It is well absorbed from the gastro-intestinal tract resulting in a greater bioavailiability of ampicillin than can be achieved with equivalent d
Publikováno v:
Antimicrobial agents and chemotherapy. 17(6)
Alafosfalin is a phosphonodipeptide with significant activity as an antibacterial agent and as a potentiator of beta-lactam antibiotics. Studies in humans showed that oral doses of 50 to 2,500 mg were well absorbed, but some metabolic hydrolysis occu
Autor:
L J, Lees
Publikováno v:
The British journal of clinical practice. 28(10)
Autor:
J W, Harding, L J, Lees
Publikováno v:
The Practitioner. 209(251)