Zobrazeno 1 - 10
of 10
pro vyhledávání: '"L J, Suva"'
Autor:
W P, Prichett, A J, Patton, J A, Field, K A, Brun, J G, Emery, K B, Tan, D J, Rieman, H A, McClung, D P, Nadeau, J L, Mooney, L J, Suva, M, Gowen, M E, Nuttall
Publikováno v:
Journal of cellular biochemistry. 76(4)
Bipotential cells in human trabecular bone explant cultures that express osteoblast characteristics are able to undergo adipogenesis in the presence of 3-isobutyl-1-methylxanthine plus dexamethasone (Nuttall et al. [1998] J Bone Miner Res 13:371-382)
Publikováno v:
Journal of cellular biochemistry. 74(4)
Commitment of members of the monocyte/macrophage family to the bone resorptive phenotype, in vitro, requires contact, of these osteoclast precursors, with osteoblasts or related stromal cells. The osteoclast-inductive properties of these stromal cell
Autor:
L. J. Suva
Publikováno v:
Novel Approaches to Treatment of Osteoporosis ISBN: 9783662090091
The primary objective of the investigation of the fundamental nature of ligand-receptor interactions is elucidation of the mechanism of ligand recognition and receptor activation. In the case of parathyroid hormone (PTH) and PTH-related protein (PTHr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6adf54c59d03934f00fe12d28b02885d
https://doi.org/10.1007/978-3-662-09007-7_10
https://doi.org/10.1007/978-3-662-09007-7_10
Autor:
W F, Schwindinger, J, Fredericks, L, Watkins, H, Robinson, J M, Bathon, M, Pines, L J, Suva, M A, Levine
Publikováno v:
Endocrine. 8(2)
Parathyroid hormone (PTH) elicits many of its physiological effects by activating distinct, G-protein-coupled signaling cascades that lead to synthesis of cyclic AMP and hydrolysis of phosphatidylinositol 4,5-bisphosphate. Using the nonhydrolyzable p
Autor:
L J, Suva, M S, Flannery, M P, Caulfield, D M, Findlay, H, Jüppner, S R, Goldring, M, Rosenblatt, M, Chorev
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
Calcitonin (CT) is a 32-amino-acid calciotropic peptide hormone which acts on target cells via a G protein-coupled seven-transmembrane receptor (CTR). In this study, we report the design, synthesis and characterization of four potent bioactive and ph
Publikováno v:
The Australian and New Zealand journal of surgery. 54(1)
Studies by this laboratory have demonstrated the presence of specific, high affinity 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) receptors both in surgical specimens of human breast cancer and in breast cancer cells in culture. We report here that 1,25-(
Publikováno v:
Cancer research. 41(12 Pt 1)
Receptors for 1,25-dihydroxyvitamin D3 have been shown to exist in cultured breast cancer cells and in primary breast cancers. It is reported here that 1,25-dihydroxyvitamin D3 receptor (1,25-DR) was present in 80% of 54 unselected breast cancers. Th
Publikováno v:
Cancer research. 46(10)
Specific high affinity receptors for 1,25-dihydroxyvitamin D3 are present in several human breast cancer cell lines, and this hormone can regulate the replication of these cells. These receptors are also present in primary breast carcinomas. The pres
Autor:
T J, Martin, L J, Suva
Publikováno v:
Bailliere's clinical endocrinology and metabolism. 2(4)
Many factors, such as interleukin 1, transforming growth factor alpha, tumour necrosis factor alpha and beta, and prostaglandins, have been implicated in the pathogenesis of the humoral hypercalcaemia of malignancy (Mundy and Martin, 1982; Martin and
Publikováno v:
Cancer research. 42(3)
Receptors for 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] have been described in several human breast cancer cell lines and more recently in human melanoma. The presence of 1,25-(OH)2D3 receptor (1,25-DR) in two cultured breast cancer cell lines was asso