Zobrazeno 1 - 10
of 24
pro vyhledávání: '"L J, Schaaf"'
Autor:
L. J. Schaaf
Publikováno v:
Transactions of the Royal Society of South Africa. 49:87-102
SUMMARY John Herschel's use of the camera lucida as a drawing aid and the part played by this instrument in Henry Fox Talbot's motivation to invent photography are described. Herschel's seminal contributions to the early progress of photography, his
Autor:
R. G. Petit, J. G. Kuhn, David Rinaldi, Langdon L. Miller, Lisa A. Hammond, Stephanie Hodges, G. I. Rodriguez, Miguel A. Villalona-Calero, S. G. Eckhardt, D. D. Von Hoff, L. J. Schaaf, Mace L. Rothenberg, Paula K. Locker, Gary Elfring, Abhishek Sharma
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 12(11)
Summary Objectives This trial was performed to determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetic profile of irinotecan (CPT-11) when administered on a once-every-2-week schedule Patients and methods CPT-11
Autor:
H C, Pitot, R M, Goldberg, J M, Reid, J A, Sloan, P A, Skaff, C, Erlichman, J, Rubin, P A, Burch, A A, Adjei, S A, Alberts, L J, Schaaf, G, Elfring, L L, Miller
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
A Phase I study was performed to determine the maximum tolerated dose (MTD), toxicities, and pharmacokinetic profile of irinotecan (CPT-11) and its active metabolites when given on a once-every-3-week schedule. Thirty-four patients with advanced refr
Autor:
J G, Slatter, L J, Schaaf, J P, Sams, K L, Feenstra, M G, Johnson, P A, Bombardt, K S, Cathcart, M T, Verburg, L K, Pearson, L D, Compton, L L, Miller, D S, Baker, C V, Pesheck, R S, Lord
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(4)
This study determined the disposition of irinotecan hydrochloride trihydrate (CPT-11) after i.v. infusion of 125 mg/m(2) (100 microCi) [(14)C]CPT-11 in eight patients with solid tumors. Mean +/- S.D. recovery of radioactivity in urine and feces was 9
Autor:
M L, Rothenberg, J G, Kuhn, L J, Schaaf, R L, Drengler, S G, Eckhardt, M A, Villalona-Calero, L, Hammond, L L, Miller, R G, Petit, E K, Rowinsky, D D, Von Hoff
Publikováno v:
Oncology (Williston Park, N.Y.). 12(8 Suppl 6)
Most of the clinical experience with irinotecan (CPT-11 [Camptosar]) has been with either a weekly or an every-3-week schedule. Recent phase I trials have explored new routes and schedules of administration. One approach attempts to maximize dose fre