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Generation of HER-2/neu-specific cytotoxic neutrophils in vivo: efficient arming of neutrophils by combined administration of granulocyte colony-stimulating factor and Fcgamma receptor I bispecific antibodies

Autor: I A Heijnen, L J Rijks, A Schiel, B Stockmeyer, H H van Ojik, M Dechant, T Valerius, T Keler, A L Tutt, M J Glennie, E A van Royen, P J Capel, J G van de Winkel

Publikováno v: The Journal of Immunology. 159:5629-5639

Abs are able to induce inflammatory antitumor responses by recruiting IgG Fc receptor (FcgammaR)-bearing cytotoxic effector cells. We recently described the capacity of the high affinity FcgammaRI (CD64) to trigger cytotoxic activity of neutrophils (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24aa769022d78f08c755736be8f2dc14
https://doi.org/10.4049/jimmunol.159.11.5629

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In vitro and in vivo characterization of newly developed iodinated 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazine derivatives in rats: limited value as dopamine transporter SPECT ligands

Autor: L J, Rijks, J, Booij, T, Doornbos, G J, Boer, E, Ronken, K, de Bruin, R J, Vermeulen, A G, Janssen, E A, Van Royen

Publikováno v: Synapse (New York, N.Y.). 23(3)

A series of 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazines (CYD1, 2, 3, 5) with a 4-substituent incorporating a 1-hydroxy-3-iodo-2-propenyl moiety, except CYD2 which lacks the hydroxy, was synthesized as potential in vivo imaging ligands for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::670b01f82cab0e69db2a52dde50d5a27
https://pubmed.ncbi.nlm.nih.gov/8807748

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