Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L J, Pluta"'
Publikováno v:
Molecular carcinogenesis. 20(3)
Quantitative differences in the expression of oncogenes are a critical feature of the cancer process. Several methods are currently available for assessing differential gene expression, but none can be used to determine quantitative changes in gene e
Publikováno v:
Environmental and molecular mutagenesis. 28(4)
1,3-Butadiene (BD) is a carcinogen that is bioactivated to at least two genotoxic metabolites. In the present article, we review briefly our previous studies on the in vivo mutagenicity and mutational spectra of BD in bone marrow and extend these stu
Publikováno v:
IARC scientific publications. (127)
We have examined the mutagenicity of 1,3-butadiene in vivo in transgenic mice constructed with lambda phage shuttle vectors that contain either lacZ or lacI as transgenes. Thus far, we have shown that butadiene is mutagenic to the lung of lacZ mice (