Zobrazeno 1 - 10
of 184
pro vyhledávání: '"L J, Old"'
Autor:
Ronald D. Finn, P. M. Deckert, Richards Elizabeth C, Nicholas J. Montalto, M. A. Clark, C. Williams, Sydney Welt, Achim A. Jungbluth, Katherine S. Panageas, L. J. Old
Publikováno v:
International Journal of Cancer. 87:382-390
Therapeutic proteins have been conjugated with polyethylene glycol (PEGylation) to reduce immunogenicity and enhance circulating dose. Here we have investigated the effect of PEGylation on immunogenicity, pharmacokinetics, and histologic microdistrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be921de45d9b3df15a3a9a9984577e32
https://doi.org/10.1002/1097-0215(20000801)87:3<382::aid-ijc12>3.0.co
https://doi.org/10.1002/1097-0215(20000801)87:3<382::aid-ijc12>3.0.co
Autor:
Elizabeth Stockert, Kristin Iversen, D McGregor, Keren Coplan, L. J. Old, Klaus J. Busam, Achim A. Jungbluth, Yao-Tseng Chen
Publikováno v:
The American Journal of Surgical Pathology. 22:57-63
The Melan-A (MART-1) gene encodes an antigen recognized by cytotoxic T cells. It has been said to be restricted in its expression to melanocytes. However, here we report the presence of immunoreactivity for A103, an antibody to Melan-A, in five adren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93637b881b9d482ecec8a9a2e44fb455
https://doi.org/10.1097/00000478-199801000-00007
https://doi.org/10.1097/00000478-199801000-00007
Publikováno v:
Cytogenetic and Genome Research. 79:237-240
CTAG was initially cloned from an esophageal squamous cell carcinoma cDNA expression library by immunoscreening with autologous patient’s serum. CTAG mRNA is expressed in a proportion of human cancers in a lineage-nonspecific fashion, whereas its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e49d79b071782fc333533353077f1b
https://doi.org/10.1159/000134734
https://doi.org/10.1159/000134734
Autor:
J S Germain, L. J. Old, Nancy E. Kemeny, Ronald D. Finn, Chaitanya R. Divgi, Andrew M. Scott, Farhad Daghighian, Steven M. Larson, Richards Elizabeth C, Sydney Welt
Publikováno v:
Journal of Clinical Oncology. 14:1787-1797
PURPOSE A phase I/II study was designed to determine the maximum-tolerated dose (MTD) of iodine 125-labeled monoclonal antibody A33 (125I-mAb A33), its limiting organ toxicity, and the uptake and retention of radioactivity in tumor lesions. PATIENTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f7f519bd3c273ceafc08316b6a85d8
https://doi.org/10.1200/jco.1996.14.6.1787
https://doi.org/10.1200/jco.1996.14.6.1787
Autor:
Steven M. Larson, Michael M. Graham, P. Garin-Chesa, Ronald D. Finn, Sydney Welt, Elizabeth A. Carswell, Alfred M. Cohen, Chaitanya R. Divgi, Andrew M. Scott, L. J. Old
Publikováno v:
Journal of Clinical Oncology. 12:1193-1203
PURPOSE To define the toxicity, imaging, and biodistribution characteristics of iodine 131-labeled monoclonal antibody F19 (131I-mAbF19). MAbF19 recognizes the fibroblast activation protein (FAP), a cell-surface glycoprotein not present in most norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cc755a678c8b21a20b64e17eaa4453
https://doi.org/10.1200/jco.1994.12.6.1193
https://doi.org/10.1200/jco.1994.12.6.1193
Publikováno v:
Journal of Clinical Oncology. 9:1749-1756
We used monoclonal antibodies to identify occult micrometastases in the bone marrow of 49 patients with operable (stage I and II) breast carcinoma. Follow-up (mean, 29 months; median, 30 months) revealed that 12 patients recurred. The presence of bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c293ec843fca08e60906153f18bd6a8
https://doi.org/10.1200/jco.1991.9.10.1749
https://doi.org/10.1200/jco.1991.9.10.1749
Autor:
M. B. Moloney, H. Kalnins, Ian D. Davis, A. Sjolander, Yao-Tseng Chen, L. J. Old, Jonathan Cebon, Geoff Dumsday, W. Woods, Gerd Ritter, J. Rood, Andrew M. Scott, Glenn A Cartwright, Simon Green, Eric W. Hoffman, Roger Murphy, Darryl W. Maher, K. Healey, A. Kypridis, David Ryan, Leonard Cohen, Michael R. Rubira, Michael K. McNamara, Eugene Maraskovsky, J. Ackland
Publikováno v:
Preparative biochemistrybiotechnology. 35(2)
The cancer‐testis antigen, NY‐ESO‐1, has been engineered into a bacterial expression plasmid which incorporates a His6‐tag. The plasmid was transfected into E. coli strain BL21 and Master and Working cell banks generated from this expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb24936a1a6c93dfb4cdfe6a6581850d
https://pubmed.ncbi.nlm.nih.gov/15881594
https://pubmed.ncbi.nlm.nih.gov/15881594
Autor:
L J, Old
Publikováno v:
Cancer immunity. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad7739cf7bbeccf41c1f65ee607d8791
https://pubmed.ncbi.nlm.nih.gov/12747762
https://pubmed.ncbi.nlm.nih.gov/12747762