Zobrazeno 1 - 10
of 11
pro vyhledávání: '"L J, Muglia"'
Publikováno v:
Clinical Pharmacology & Therapeutics. 93:204-211
The Vanderbilt DNA repository, BioVU, links DNA from leftover clinical blood samples to de-identified electronic medical records (EMRs). After initiating adult sample collection, pediatric extension required consideration of ethical concerns specific
Autor:
Susan J. Kim, L. J. Muglia, Ping Li, S. K. Vogt, Min Zhuo, D. A. Robinson, G. D. Wang, Feng Wei
Publikováno v:
The Journal of Physiology. 540:593-606
As a neurohormone and as a neurotransmitter, oxytocin has been implicated in the stress response. Descending oxytocin-containing fibres project to the dorsal horn of the spinal cord, an area important for processing nociceptive inputs. Here we tested
Publikováno v:
Endocrine Research. 26:1057-1066
Corticotropin-releasing hormone (CRH)-deficient (knockout (KO)) mice demonstrate severely impaired adrenal responses to restraint, ether, and fasting, and lack the normal diurnal glucocorticoid (GC) rhythm. Here, we summarize recent studies determini
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 117(8)
To evaluate pregnancy outcomes in normotensive second pregnancy following pre-eclampsia in first pregnancy.Population-based retrospective cohort study.State of Missouri in the USA.White European origin or African-American women who delivered their fi
Autor:
Kenneth S. Korach, Sonoko Ogawa, Elena Choleris, Martin Kavaliers, L. J. Muglia, Jan-Ake Gustafsson, Donald W. Pfaff
Publikováno v:
Genes, brain, and behavior. 5(7)
Social recognition, processing, and retaining information about conspecific individuals is crucial for the development of normal social relationships. The neuropeptide oxytocin (OT) is necessary for social recognition in male and female mice, with it
Autor:
A K, Ragnauth, N, Devidze, V, Moy, K, Finley, A, Goodwillie, L-M, Kow, L J, Muglia, D W, Pfaff
Publikováno v:
Genes, brain, and behavior. 4(4)
Compared to results from a generation of neuropharmacological work, the phenotype of mice lacking the oxytocin (OT) peptide gene was remarkably normal. An important component of the current experiments was to assay OT-knockout (OTKO) and wild-type (W
Autor:
L. J. Muglia, Donald W. Pfaff, Jan-Åke Gustafsson, K. S. Korach, Martin Kavaliers, Anders Ågmo, Sonoko Ogawa, Elena Choleris
Publikováno v:
Genes, brain, and behavior. 3(4)
Social behavior involves both the recognition and pro-duction of social cues. Mice with selective deletion(knockout) of either the gene for oxytocin (OT) or genes for the estrogen receptor (ER) -c or -B display impaired social recognition. In this st
Publikováno v:
Journal of neuroendocrinology. 15(11)
The neuropeptide oxytocin is released not only into the blood, but also within the brain in response to various stressors. Accumulating evidence suggests that central oxytocin may play a major role in the regulation of neuroendocrine responses to str
Publikováno v:
Genes, brain, and behavior. 2(4)
A major cost of social behavior is the increased risk of exposure to parasites, with animals utilizing social information to recognize and avoid infected conspecifics. In mice, females can discriminate between infected and uninfected males on the bas
Publikováno v:
Endocrine research. 28(4)
To determine the cellular targets for glucocorticoid (GC) action, we have generated mice in which a green fluorescent protein-glucocorticoid receptor (GFP-GR) fusion gene is knocked into the endogenous GR locus. We found that GFP-GR function is indis