Zobrazeno 1 - 10
of 27
pro vyhledávání: '"L J, McNeilage"'
Publikováno v:
Clinical and Experimental Immunology. 101:39-44
SUMMARY In systemic autoimmunity, the human B cell response to the La (SS-B) autoantigen is polyclonal and directed to both conserved and human-specific epitopes. This study has further characterized the B cell epitope(s) present within the conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3be64a169e0c2a0f0c6a00837bbe168
https://doi.org/10.1111/j.1365-2249.1995.tb02274.x
https://doi.org/10.1111/j.1365-2249.1995.tb02274.x
Publikováno v:
The Journal of Immunology. 151:6872-6881
Autoantibodies that react with the nuclear enzyme topoisomerase I (Topo I) are used as a diagnostic marker of diffuse scleroderma. To better define immune reactivity to Topo I, antibody epitopes in two patient populations were analyzed using recombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a6e280898a6e95ff05787401d95552d
https://doi.org/10.4049/jimmunol.151.12.6872
https://doi.org/10.4049/jimmunol.151.12.6872
Autor:
L J McNeilage, A J Barnett
Publikováno v:
Annals of the Rheumatic Diseases. 52:365-368
OBJECTIVE--To test the postulate that there is a higher prevalence of antinuclear antibodies (ANAs) in serum samples from blood relatives and from spouses of patients with scleroderma than in control samples, and that this provides evidence for both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7530e2080e4db33bdf97d2e47f806f
https://doi.org/10.1136/ard.52.5.365
https://doi.org/10.1136/ard.52.5.365
Autor:
L J McNeilage, Kandiah Umapathysivam, Tom P. Gordon, Elizabeth Macmillan, S Whittingham, A. Guidolin
Publikováno v:
Journal of Clinical Investigation. 89:1652-1656
High-titer IgG autoantibodies to the La/SS-B ribonucleoprotein (RNP) are a hallmark of patients with primary Sjogren's syndrome. Anti-La/SS-B-positive human sera bind to multiple epitopes on recombinant La/SS-B, although the initial response is again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fb8b94ee21b47145af6ce0a27ecd58
https://doi.org/10.1172/jci115762
https://doi.org/10.1172/jci115762
Publikováno v:
Clinical and Experimental Immunology. 85:402-406
SUMMARYThe contribution of circulating anti-La(SS-B) antibody to the hypergammaglobulinaemia seen in primary Sjögren’s syndrome is unknown. In this study levels of anti-La(SS-B) antibody directed against three immunodominant epitopes of the anti-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aac56fb5fa2d832325c1fd33d99b7ec
https://doi.org/10.1111/j.1365-2249.1991.tb05739.x
https://doi.org/10.1111/j.1365-2249.1991.tb05739.x
Publikováno v:
The Journal of Immunology. 145:3829-3835
Autoepitopes on the ribonucleoprotein La(SS-B) were identified by using recombinant La(SS-B) polypeptides and sera from 166 patients with the antinuclear autoantibody anti-La(SS-B). The La(SS-B) polypeptides were encoded by polymerase chain reaction-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af21b6b1f79309b1b5ff7de92867ab0
https://doi.org/10.4049/jimmunol.145.11.3829
https://doi.org/10.4049/jimmunol.145.11.3829
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(12)
Autoantibodies that react with the nuclear enzyme topoisomerase I (Topo I) are used as a diagnostic marker of diffuse scleroderma. To better define immune reactivity to Topo I, antibody epitopes in two patient populations were analyzed using recombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2b29fe3877f8003bcb8391c765a3d0d
https://pubmed.ncbi.nlm.nih.gov/7505017
https://pubmed.ncbi.nlm.nih.gov/7505017
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(11)
Autoepitopes on the ribonucleoprotein La(SS-B) were identified by using recombinant La(SS-B) polypeptides and sera from 166 patients with the antinuclear autoantibody anti-La(SS-B). The La(SS-B) polypeptides were encoded by polymerase chain reaction-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09ef7a2f00160c67b7dabc130119a5d1
https://pubmed.ncbi.nlm.nih.gov/1700996
https://pubmed.ncbi.nlm.nih.gov/1700996
Publikováno v:
The Journal of Immunology. 140:3212-3218
The La (SS-B) polypeptide is a ribonucleoprotein against which high titer antinuclear antibodies (ANA) react in the human autoimmune disease primary Sjögren's syndrome. To identify the autoepitopes with which the ANA anti-La (anti-SS-B) reacts, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b0931cc62ca214c75128136f3b3156
https://doi.org/10.4049/jimmunol.140.9.3212
https://doi.org/10.4049/jimmunol.140.9.3212
Publikováno v:
Cellular Immunology. 72:340-350
The term natural cytotoxicity (NC) describes a phenomenon in rats whereby significant numbers of intravenously injected 51 Cr-labeled lymph node cells are rapidly destroyed by unsensitized allogeneic hosts. Cell death is reflected in a decreased accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011c4bcd8955de541d87b7d4a6c7b148
https://doi.org/10.1016/0008-8749(82)90482-8
https://doi.org/10.1016/0008-8749(82)90482-8