Modeling the Cancer Stem Cell Hypothesis

Autor: C. Calmelet, L. J. McCawley, J. Mensah, Philip S. Crooke, A. Prokop

Publikováno v: Mathematical Modelling of Natural Phenomena. 5:40-62

Solid tumors and hematological cancers contain small population of tumor cells that are believed to play a critical role in the development and progression of the disease. These cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::820ac564c22b81e01d98aefe6f9cbc2c
https://doi.org/10.1051/mmnp/20105304

Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration

Autor: L J, McCawley, S, Li, E V, Wattenberg, L G, Hudson

Publikováno v: The Journal of biological chemistry. 274(7)

Activation of the extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway is required for ligand-dependent regulation of numerous cellular functions by receptor tyrosine kinases. We have shown previously that altho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70fedc5be8c63c5a1ced50777f90626b
https://pubmed.ncbi.nlm.nih.gov/9933637

Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)- mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9

Autor: L J, McCawley, P, O'Brien, L G, Hudson

Publikováno v: Journal of cellular physiology. 176(2)

Receptor tyrosine kinases are key regulators of cellular function including cell growth, differentiation, migration, and morphogenesis. Disruptions of receptor tyrosine kinase signaling pathways are often associated with changes in cellular prolifera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3b77302d71e39bd4a17e9843c4d84c7d
https://pubmed.ncbi.nlm.nih.gov/9648913

Using Human‐Induced Pluripotent Stem Cell Derived Neurons on Microelectrode Arrays to Model Neurological Disease: A Review.

Autor: Lv, Shiya^1,2 (AUTHOR), He, Enhui^1,2,3 (AUTHOR), Luo, Jinping^1,2 (AUTHOR), Liu, Yaoyao^1,2 (AUTHOR), Liang, Wei^1,2 (AUTHOR), Xu, Shihong^1,2 (AUTHOR), Zhang, Kui^1,2 (AUTHOR), Yang, Yan^1,2 (AUTHOR), Wang, Mixia^1,2 (AUTHOR), Song, Yilin^1,2 (AUTHOR) ylsong@mail.ie.ac.cn, Wu, Yirong^1,2 (AUTHOR) wyr@mail.ie.ac.cn, Cai, Xinxia^1,2 (AUTHOR) xxcai@mail.ie.ac.cn

Publikováno v: Advanced Science. 11/24/2023, Vol. 10 Issue 33, p1-23. 23p.

Engineering Neurovascular Unit and Blood-Brain Barrier for Ischemic Stroke Modeling.

Autor: Liu Z; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China., Tang Y; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China., Zhang Z; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China., Liu Q; Ankerui (Shanxi) Biological Cell Co., Ltd. , Shanxi, 030000, China., Wang M; Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Science and Technology, Tongji University, Shanghai, 200065, China., Li W; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China., Yang GY; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2023 Jul; Vol. 12 (19), pp. e2202638. Date of Electronic Publication: 2023 May 01.