Zobrazeno 1 - 10
of 95
pro vyhledávání: '"L J, Marnett"'
Publikováno v:
Biochemistry. 40:3109-3116
Cyclooxygenase is involved in the biosynthesis and function of prostaglandins. It is a glycoprotein located in the endoplasmic reticulum and in the nuclear envelope, and it has been found to have two isoforms termed COX-1 and COX-2. This paper report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54fe541df812056e624a561bf08ee8b9
https://doi.org/10.1021/bi002313c
https://doi.org/10.1021/bi002313c
Publikováno v:
Journal of Biological Chemistry. 268:1708-1715
13(S)-Hydroperoxyoctadeca-9(Z),11(E),15(Z)-trienoic acid (13-HPOT) was used to probe the mechanism of the hydroperoxide O-O bond cleavage catalyzed by solubilized and partially purified soybean peroxygenase. When reacted with this ferrihemoprotein, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9cb7d8072dccdb9421e3ceafd360d4
https://doi.org/10.1016/s0021-9258(18)53910-7
https://doi.org/10.1016/s0021-9258(18)53910-7
Autor:
L J Marnett, J.F. Curtis, T A Kennedy, G. Lassmann, Thomas E. Eling, J A DeGray, Ronald P. Mason
Publikováno v:
ResearcherID
We have analyzed the low temperature EPR spectra of the protein-derived tyrosyl radicals detected upon addition of arachidonic acid or 5-phenyl-4-pentenyl-1-hydroperoxide (PPHP) to prostaglandin H synthase. With either arachidonic acid or PPHP the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5ed5bbab607ef879e97ee662457908
https://doi.org/10.1016/s0021-9258(18)35878-2
https://doi.org/10.1016/s0021-9258(18)35878-2
Autor:
G. Lassmann, Ronald P. Mason, Thomas E. Eling, R Odenwaller, J.F. Curtis, J A DeGray, L J Marnett
Publikováno v:
ResearcherID
We have examined, by low temperature ESR, the protein-derived radicals formed by reaction of purified ram seminal vesicle prostaglandin H synthase (PHS). Upon addition of arachidonic acid or 5-phenyl-4-pentenyl-1-hydroperoxide (PPHP) to PHS reconstit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132659ba64da0846776b6d8a1bf248cc
https://doi.org/10.1016/s0021-9258(18)54889-4
https://doi.org/10.1016/s0021-9258(18)54889-4
Autor:
M B, Kadiiska, B C, Gladen, D D, Baird, L B, Graham, C E, Parker, B N, Ames, S, Basu, G A, Fitzgerald, J A, Lawson, L J, Marnett, J D, Morrow, D M, Murray, J, Plastaras, L J, Roberts, J, Rokach, M K, Shigenaga, J, Sun, P B, Walter, K B, Tomer, J C, Barrett, R P, Mason
Publikováno v:
Free radical biologymedicine. 38(6)
Plasma and urinary levels of malondialdehyde-like products (MDA) and isoprostanes were identified as markers of in vivo lipid peroxidation in an animal model of CCl4 poisoning. We sought to determine the extent to which the formation of these oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40a7ae9e59ececc448887c8faaf16fb2
https://pubmed.ncbi.nlm.nih.gov/15721981
https://pubmed.ncbi.nlm.nih.gov/15721981
Autor:
T B, Adams, J, Doull, V J, Feron, J I, Goodman, L J, Marnett, I C, Munro, P M, Newberne, P S, Portoghese, R L, Smith, W J, Waddell, B M, Wagner
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 40(4)
This is the fifth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35f3c579025ba0c7848550df19ce4816
https://pubmed.ncbi.nlm.nih.gov/11893403
https://pubmed.ncbi.nlm.nih.gov/11893403
Publikováno v:
Advances in experimental medicine and biology. 500
Malondialdehyde (MDA) is a toxic and mutagenic metabolite produced by lipid peroxidation, and prostaglandin biosynthesis. MDA induces frameshift mutations in tester strains of Salmonella typhimurium. It reacts with DNA, and at physiological pH the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c26256a959c1d760ff314c718f162ff
https://pubmed.ncbi.nlm.nih.gov/11764989
https://pubmed.ncbi.nlm.nih.gov/11764989
Publikováno v:
Advances in experimental medicine and biology. 500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f6c24f3b2672676aec55943583f8e7d
https://pubmed.ncbi.nlm.nih.gov/11764925
https://pubmed.ncbi.nlm.nih.gov/11764925
Publikováno v:
Biochemistry. 40(51)
The pyrimidopurinone adduct M1G [3-(2'-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-a]-purin-10(3H)-one], formed in DNA upon exposure to malondialdehyde or base propenals, was incorporated into 5'-d(ATCGCMCGGCATG)-3'-5'-d(CATGCCGCGAT)-3', where M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::743943b5a208bb828a20a611dced67b0
https://pubmed.ncbi.nlm.nih.gov/11747439
https://pubmed.ncbi.nlm.nih.gov/11747439
Autor:
R A, Sharma, C R, Ireson, R D, Verschoyle, K A, Hill, M L, Williams, C, Leuratti, M M, Manson, L J, Marnett, W P, Steward, A, Gescher
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
Curcumin prevents colon cancer in rodent models. It inhibits lipid peroxidation and cyclooxygenase-2 (COX-2) expression and induces glutathione S-transferase (GST) enzymes. We tested the hypothesis that 14 days of dietary curcumin (2%) affects biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afe61499bd53d09dd1d73aea5682a32b
https://pubmed.ncbi.nlm.nih.gov/11350917
https://pubmed.ncbi.nlm.nih.gov/11350917