Zobrazeno 1 - 10
of 37
pro vyhledávání: '"L J, Guilbert"'
Publikováno v:
The Journal of Immunology. 156:653-662
Maternal immune responses can influence fetal survival and several cytokines have harmful or protective effects on pregnancy. The Th1 cytokines IFN-gamma and IL-2 can cause fetal loss, whereas the Th2 cytokine IL-10 is protective. However, infections
Publikováno v:
The Journal of Immunology. 156:644-652
Resolution of cutaneous leishmaniasis in infected mice is associated with a polarized Th1 immune response by the host, whereas maternal immune responses during pregnancy appear to be biased toward humoral (Th2) and away from cell-mediated (Th1) respo
Publikováno v:
Journal of leukocyte biology. 68(6)
Placental inflammations (villitis) are accompanied by loss of the syncytiotrophoblast, which is the cellular barrier separating maternal blood from fetal tissue in the villous placenta. We propose that syncytiotrophoblast loss is mediated by adhesion
Publikováno v:
Biology of reproduction. 63(5)
The large increase in placental surface area and fetal villous vascular development in the third trimester of pregnancy requires degradation and reformation of the placental basal lamina. Degradation is carried out by matrix metalloproteinases (MMPs)
Publikováno v:
Journal of cellular physiology. 180(2)
The activation of sphingomyelinase and the subsequent generation of ceramide are emerging as important components of signaling pathways leading to apoptosis. The combination of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma)
Publikováno v:
Biology of reproduction. 60(5)
Trophoblasts, the fetal cells that line the villous placenta and separate maternal blood from fetal tissue, express both Fas antigen and the tumor necrosis factor (TNF) receptor p55 (TNFRp55), two members of the TNF receptor family that contain a cyt
Autor:
J J, Ramsoondar, R J, Christopherson, L J, Guilbert, W T, Dixon, A, Ghahary, S, Ellis, T G, Wegmann, J A, Piedrahita
Publikováno v:
Biology of reproduction. 60(2)
In this study, the pattern of expression of class I major histocompatibility (MHC) antigens and mRNA on periimplantation blastocysts and term placental tissue was determined for the pig. Class I MHC antigens could not be detected immunohistochemicall
Publikováno v:
Scopus-Elsevier
Late stages of Plasmodium falciparum-infected erythrocytes (IRBCs) frequently sequester in the placentas of pregnant women, a phenomenon associated with low birth weight of the offspring. To investigate the physiological mechanism of this sequestrati
Publikováno v:
Biology of reproduction. 55(2)
Tumor necrosis factor alpha (TNF alpha) induces the apoptotic death of primary villous cytotrophoblasts in culture (Yui et al., Placenta 1994; 15:819). Since both p55 and p75 TNF receptors (TNFRs) localize to the villous trophoblast, we examined thei
Publikováno v:
Journal of cellular physiology. 167(2)
In the placenta, as in other organs, the development and maintenance of the differentiated phenotype depend on a balance between cell proliferation, maturation, and death. We are interested in the mechanisms that regulate the survival and differentia