Výsledky vyhledávání

Prognostic significance of circulating microsatellite markers in the plasma of melanoma patients

Autor: B, Taback, Y, Fujiwara, H J, Wang, L J, Foshag, D L, Morton, D S, Hoon

Publikováno v: Cancer research. 61(15)

Multiple genetic alterations including loss of heterozygosity (LOH) occur commonly in melanoma tumors. We demonstrated previously free-circulating DNA microsatellites with LOH in the blood of melanoma patients. These LOH markers in plasma may be usef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8472af1cdf83897a7d68c2b2d73ffd98
https://pubmed.ncbi.nlm.nih.gov/11479206

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Focused examination of sentinel lymph nodes upstages early colorectal carcinoma

Autor: T F, Wood, G J, Tsioulias, D L, Morton, D, Rangel, W, Hutchinson, L J, Foshag, R R, Turner, A J, Bilchik

Publikováno v: The American surgeon. 66(11)

Approximately 30 per cent of patients with early colorectal carcinoma (CRC) develop systemic disease. A subgroup of these patients may harbor occult micrometastatic disease and might benefit from adjuvant chemotherapy. We investigated sentinel lymph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1966fb0299eba24794e68fa86d8d22f
https://pubmed.ncbi.nlm.nih.gov/11090005

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Active specific immunotherapy with polyvalent melanoma cell vaccine for patients with in-transit melanoma metastases

Autor: E C, Hsueh, L, Nathanson, L J, Foshag, R, Essner, J A, Nizze, S L, Stern, D L, Morton

Publikováno v: Cancer. 85(10)

This study was conducted to document the rate, duration, and type of objective response to active specific immunotherapy with a polyvalent melanoma cell vaccine (PMCV) for patients with in-transit melanoma metastases and to identify any acute or chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e93d3bca53600e6c325bc888b725e1b3
https://pubmed.ncbi.nlm.nih.gov/10326694

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Universal application of intraoperative lymphatic mapping and sentinel lymphadenectomy in solid neoplasms

Autor: A J, Bilchik, A, Giuliano, R, Essner, P, Bostick, P, Kelemen, L J, Foshag, S, Sostrin, R R, Turner, D L, Morton

Publikováno v: The cancer journal from Scientific American. 4(6)

Regional lymph node involvement is the most important prognostic indicator in patients with solid tumors. Conventional lymph node dissection has not been shown to affect survival and is often associated with considerable morbidity. Intraoperative lym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b7edae7f07c242cc2e055acffcd401f
https://pubmed.ncbi.nlm.nih.gov/9853133

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Polyvalent melanoma cell vaccine induces delayed-type hypersensitivity and in vitro cellular immune response

Autor: A, Barth, D S, Hoon, L J, Foshag, J A, Nizze, E, Famatiga, E, Okun, D L, Morton

Publikováno v: Cancer research. 54(13)

Patients with melanoma metastatic to distant sites or at high risk for recurrent melanoma have been treated with a polyvalent melanoma cell vaccine (MCV) in phase II protocols. We assessed in vivo and in vitro cell-mediated responses to MCV in 163 pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bcee1ab89da542ab1f8d1c6df59fe6d0
https://pubmed.ncbi.nlm.nih.gov/8012946

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A preclinical model to assess the antigenicity of an HLA-A2 melanoma cell vaccine

Autor: Y, Hayashi, D S, Hoon, L J, Foshag, M S, Park, P I, Terasaki, D L, Morton

Publikováno v: Cancer. 72(3)

The authors have demonstrated that immunization with melanoma whole-cell vaccine (MCV) augments T-cell responses to melanoma and that cytotoxic T-cells (CTL) recognize allogeneic melanoma-bearing shared HLA-A antigens. A preclinical model was develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e72e52afc347495107b0c1e1ea0ff1b
https://pubmed.ncbi.nlm.nih.gov/8334627

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Multivariate analysis of the relationship between survival and the microstage of primary melanoma by Clark level and Breslow thickness

Autor: D L, Morton, D G, Davtyan, L A, Wanek, L J, Foshag, A J, Cochran

Publikováno v: Cancer. 71(11)

The American Joint Committee on Cancer (AJCC) uses both Breslow thickness and Clark level in its staging system for malignant melanoma. Stage I corresponds to Breslow thicknesses less than 1.5 mm and Clark levels II and III. Stage II corresponds to B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84e5d93a05ff43875464dc29a8ce67b0
https://pubmed.ncbi.nlm.nih.gov/8490924

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The role of surgery in the treatment of nonregionally recurrent melanoma

Autor: J H, Wong, K A, Skinner, K A, Kim, L J, Foshag, D L, Morton

Publikováno v: Surgery. 113(4)

Between 1971 and 1989, 144 patients underwent 183 surgical procedures for resection of nonregional metastatic melanoma.Thirty-six patients with subcutaneous or nodal metastases, 46 patients with pulmonary metastases, 17 patients with brain metastases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2da2840bde402691c0924d3afbbe6974
https://pubmed.ncbi.nlm.nih.gov/8456394

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Interleukin 4 receptor expression and growth inhibition of gastric carcinoma cells by interleukin 4

Autor: T, Morisaki, D H, Yuzuki, R T, Lin, L J, Foshag, D L, Morton, D S, Hoon

Publikováno v: Cancer research. 52(21)

The expression of the interleukin 4 (IL-4) receptor (IL-4R) and effects of human recombinant IL-4 on human gastric carcinoma cell lines were studied. We demonstrated that IL-4 inhibited the growth of gastric carcinoma cells in a dose dependent manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e4a2d876d7ce8faee3629002823c1a0
https://pubmed.ncbi.nlm.nih.gov/1394231

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