Zobrazeno 1 - 10
of 332
pro vyhledávání: '"L J, Findley"'
Publikováno v:
European Journal of Neurology. 12:1-8
This study examined the relative anti-Parkinson's disease (PD) tremor potencies of pergolide and pramipexole in people with PD, using a 3-month double-blind cross-over design. Patients were randomly assigned to receive either pergolide and then prami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea081b348068af8b1d7c988cb2361743
https://doi.org/10.1111/j.1468-1331.2004.01019.x
https://doi.org/10.1111/j.1468-1331.2004.01019.x
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 68:756-760
OBJECTIVES To examine the comparative reliability and validity of three simple ways of rating upper limb tremor in patients with multiple sclerosis. METHODS Three examiners independently rated severity of upper limb tremor in patients with multiple s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36ee7aa471df7235dcfe6aa2c02d476
https://doi.org/10.1136/jnnp.68.6.756
https://doi.org/10.1136/jnnp.68.6.756
Publikováno v:
Scopus-Elsevier
Primary orthostatic tremor is characterized by unsteadiness and shakiness of the legs while standing. It is due to a remarkably strong and regular EMG modulation at approximately 16 Hz that is thought to be of CNS origin. Previous studies have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ac1c9f1f3f0dd6d874395e43218ba5
https://doi.org/10.1093/brain/123.2.254
https://doi.org/10.1093/brain/123.2.254
Autor:
C. I. Dellaportas, L. J. Findley, F. B. Gibberd, D. M. Park, R. Abbott, G. D. Perkin, M. Gross, T. J. Steiner
Publikováno v:
Epilepsia. 40:601-607
Summary: Purpose: Lamotrigine is an effective add-on therapy against a range of epileptic seizure types. Comparative studies with carbamazepine (CBZ) as monotherapy in newly diagnosed epilepsy suggest similar efficacy. In this study, lamotrigine (LTG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24446afb4d97f92860aa83c25f5ffcaf
https://doi.org/10.1111/j.1528-1157.1999.tb05562.x
https://doi.org/10.1111/j.1528-1157.1999.tb05562.x
Publikováno v:
Cephalalgia. 17:109-112
Lamotrigine blocks voltage-sensitive sodium channels, leading to inhibition of neuronal release of glutamate. Release of glutamate may be essential in the propagation of spreading cortical depression, which some believe is central to the genesis of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7509561f8c3a6b9802c306947fccc87e
https://doi.org/10.1046/j.1468-2982.1997.1702109.x
https://doi.org/10.1046/j.1468-2982.1997.1702109.x
Autor:
Henning Boecker, Philip D. Thompson, M. Samuel, Andres O. Ceballos-Baumann, L. J. Findley, David J. Brooks, Adrian J. Wills
Publikováno v:
Annals of Neurology. 39:650-658
We used H2 15O positron emission tomography (PET) to investigate the effect of ethyl alcohol on regional cerebral blood flow in 6 patients with alcohol-responsive essential tremor and 6 age-matched control subjects. The patients were scanned while at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8233b1be31da1c0a5c4ce560f3646145
https://doi.org/10.1002/ana.410390515
https://doi.org/10.1002/ana.410390515
Publikováno v:
Journal of Neurology. 243:68-72
The use of a dopamine agonist with a long duration of action has theoretical advantages in attempting to reduce the motor fluctuations in Parkinson's disease. We report the results of a double-blind controlled study of adding cabergoline, an ergot de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3f76f3339093fde134f01fa93223d2
https://doi.org/10.1007/bf00878534
https://doi.org/10.1007/bf00878534
Autor:
T. C. Britton, Jc Rothwell, Pd Thompson, L. J. Findley, Michael A. Gresty, Peter G. Bain, C. D. Marsden
Publikováno v:
Brain. 118:1461-1472
Primary writing tremor (PWT) is considered to be a type of task-specific tremor in which tremor predominantly occurs and interferes with handwriting. We describe the clinical and neurophysiological features of 21 patients (20 male and one female) wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e120c5fb1a7d6f217277273e750df1
https://doi.org/10.1093/brain/118.6.1461
https://doi.org/10.1093/brain/118.6.1461
Publikováno v:
Annals of Neurology. 36:636-642
There has been debate as to whether essential tremor has a central origin and over the possible role of the inferior olivary nucleus in its genesis. We used positron emission tomography with radioactive water (H2(15)O) to detect abnormal patterns of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b8c52bca0778dccc291c07ab2ae3ac
https://doi.org/10.1002/ana.410360413
https://doi.org/10.1002/ana.410360413
Autor:
L. J. Findley, Pd Thompson, Peter G. Bain, C D Marsden, A. E. Harding, Jc Rothwell, Michael A. Gresty
Publikováno v:
Brain. 117:805-824
Twenty index patients with hereditary essential tremor and their kindreds were studied to define the phenotype of this condition. Ninety-three first degree and 38 more distant relatives were examined; 53 definite and 18 possible secondary cases were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21950a6606657f970e0746e919a97be
https://doi.org/10.1093/brain/117.4.805
https://doi.org/10.1093/brain/117.4.805