Zobrazeno 1 - 7
of 7
pro vyhledávání: '"L J, Coignet"'
Autor:
Martin J. S. Dyer, Hans G. Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod, Corinna Meyer, L. J. Coignet, J. W. G. Janssen
Publikováno v:
Leukemia. 15:1471-1474
Continuous leukemia-lymphoma cell lines are important research tools, in particular as starting material for the cloning of recurrent translocations. In 1998, we established the continuous leukemia cell line MUTZ-5. The two cell lines MUTZ-6 and MUTZ
Autor:
L J, Coignet
Publikováno v:
Methods in molecular medicine. 61
Structural and numerical chromosomal abnormalities have been observed in all types of malignancies. These events are associated with neoplastic pathogenesis and progression (1). For a long time, conventional cytogenetics analysis was the prevalent ap
Autor:
R Pramanik, A L Pontier, X M Qi, E I Cline, M.J. Fekete, Mark W. Lingen, C Brigaudeau, L J Coignet, Leslie E. Martin, Rifat Hasina
Publikováno v:
Oncogene. 25(4)
Cervical cancer is associated with human papilloma virus infection. However, this infection is insufficient to induce transformation and progression. Loss of heterozygosity analyses suggest the presence of a tumor suppressor gene (TSG) on chromosome
Autor:
M A, Yuille, L J, Coignet
Publikováno v:
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 154
The ataxia telangiectasia (A-T) gene, ATM, predisposes affected homozygotes to a wide range of malignancies. It has been suggested that this is a consequence of the genomic instability associated with the syndrome. The elevated risk of malignancy is
Autor:
T G, Willis, I R, Zalcberg, L J, Coignet, I, Wlodarska, M, Stul, D M, Jadayel, C, Bastard, J G, Treleaven, D, Catovsky, M L, Silva, M J, Dyer
Publikováno v:
Blood. 91(6)
Abnormalities of chromosome 1q21 are common in B-cell malignancies and have been associated with a poor response to therapy. The nature of the involved gene(s) on chromosome 1q21 remains unknown. A cell line (CEMO-1) has recently been established fro
Autor:
T G, Willis, D M, Jadayel, L J, Coignet, M, Abdul-Rauf, J G, Treleaven, D, Catovsky, M J, Dyer
Publikováno v:
Blood. 90(6)
Clonal rearrangements of the Ig heavy chain (IGH) locus consisting of either intrachromosomal (VDJ) rearrangements or interchromosomal translocations are a consistent feature of all B-cell malignancies and may be used both diagnostically and to monit
Autor:
L J, Coignet, E, Schuuring, R E, Kibbelaar, T K, Raap, K K, Kleiverda, M F, Bertheas, J, Wiegant, G, Beverstock, P M, Kluin
Publikováno v:
Blood. 87(4)
Rearrangements within the chromosome 11q13 region are frequent in hematologic malignancies. 50% of 75% of mantle cell lymphomas (MCLs) carry a translocation t(11;14) (q13;q32). Using Southern blot analysis, a BCL1 breakpoint can be detected in approx