Zobrazeno 1 - 10
of 232
pro vyhledávání: '"L J, Burgart"'
Autor:
L J Burgart
Publikováno v:
Mayo Clinic Proceedings. 73:479-482
Autor:
W, Müller, L J, Burgart, R, Krause-Paulus, S N, Thibodeau, M, Almeida, T B, Edmonston, C R, Boland, C, Sutter, J R, Jass, A, Lindblom, J, Lubinski, K, MacDermot, D S, Sanders, H, Morreau, A, Müller, C, Oliani, T, Orntoft, M, Ponz De Leon, C, Rosty, M, Rodriguez-Bigas, J, Rüschoff, A, Ruszkiewicz, J, Sabourin, R, Salovaara, G, Möslein
Publikováno v:
Familial cancer. 1(2)
Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is an autosomal dominant condition accounting for 2-5% of all colorectal carcinomas as well as a small subset of endometrial, upper urinary tract and other gastrointestinal cancers. An assay
Publikováno v:
Cancer. 92(1)
The CDH1 gene encodes E-cadherin, an epithelial cell adhesion molecule. Germline CDH1 mutations recently were identified in families with hereditary diffuse gastric carcinoma in a pattern suggestive of autosomal dominant inheritance with incomplete p
Autor:
L A, Boardman, S, Schmidt, N M, Lindor, L J, Burgart, J M, Cunningham, T, Price-Troska, K, Snow, D A, Ahlquist, S N, Thibodeau
Publikováno v:
Genes, chromosomescancer. 30(2)
Twenty percent of colorectal cancers (CRCs) arise in people who have a family history of CRC in at least one other relative. Although a fraction of these CRCs are explained by two well-described autosomal dominant syndromes-5% by hereditary nonpolypo
Autor:
S R, Ritland, S J, Gendler, L J, Burgart, D W, Fry, J M, Nelson, A J, Bridges, L, Andress, W E, Karnes
Publikováno v:
Cancer research. 60(17)
A highly selective, p.o. bioavailable irreversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, N-[4-(3-chloro4-fluorophenylamino)-quinazolin-6-yl]-ac rylamide (CFPQA), was evaluated for its ability to prevent intestinal aden
Autor:
Y, Maor-Kendler, K P, Batts, L J, Burgart, R H, Wiesner, R A, Krom, C B, Rosen, M R, Charlton
Publikováno v:
Transplantation. 70(2)
End-stage liver disease for which no cause can be identified, cryptogenic cirrhosis, is a common indication for liver transplantation. Allograft inflammation and fibrosis have been reported to recur with similar frequencies after liver transplantatio
Autor:
C C, Compton, L P, Fielding, L J, Burgart, B, Conley, H S, Cooper, S R, Hamilton, M E, Hammond, D E, Henson, R V, Hutter, R B, Nagle, M L, Nielsen, D J, Sargent, C R, Taylor, M, Welton, C, Willett
Publikováno v:
Archives of pathologylaboratory medicine. 124(7)
Under the auspices of the College of American Pathologists, the current state of knowledge regarding pathologic prognostic factors (factors linked to outcome) and predictive factors (factors predicting response to therapy) in colorectal carcinoma was
Autor:
L A, Boardman, F J, Couch, L J, Burgart, D, Schwartz, R, Berry, S K, McDonnell, D J, Schaid, L C, Hartmann, J J, Schroeder, C A, Stratakis, S N, Thibodeau
Publikováno v:
Human mutation. 16(1)
LKB1, the human gene encoding a serine threonine kinase, was recently identified as a susceptibility gene for Peutz-Jeghers syndrome (PJS), a disease characterized by the constellation of intestinal hamartomata, oral mucocutaneous hyperpigmentation,
Publikováno v:
Cancer research. 60(8)
Members of the protein kinase C (PKC) family appear to play important roles in colorectal carcinogenesis. To investigate the potential involvement of PKC isozymes in adenomatous transformation induced by inactivation of the adenomatous polyposis coli
Autor:
Y R, Parc, K C, Halling, L, Wang, E R, Christensen, J M, Cunningham, A J, French, L J, Burgart, T L, Price-Troska, P C, Roche, S N, Thibodeau
Publikováno v:
Cancer research. 60(8)
Two microsatellite instability (MSI) phenotypes have been described in colorectal cancer (CRC): MSI-H (instability at30% of the loci examined) and MSI-L (MSI at 1-30% of the loci examined). The MSI-H phenotype, observed in both hereditary nonpolyposi