Zobrazeno 1 - 8
of 8
pro vyhledávání: '"L J, Benjamin"'
Autor:
G Rodgers, James M. Manning, B Weksler, Klaus Schneider, Wanda M. Jones, Brian T. Chait, J J Martin de Llano, L J Benjamin
Publikováno v:
Journal of Biological Chemistry. 268:27004-27011
Previous studies had indicated that recombinant and natural human sickle hemoglobin had similar chemical properties (Martin de Llano, J. J., Schneewind, O., Stetler, G., and Manning, J. M. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 918-922). In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0114616d60a54f245f259680ece28db9
https://doi.org/10.1016/s0021-9258(19)74210-0
https://doi.org/10.1016/s0021-9258(19)74210-0
Publikováno v:
Blood. 95(4)
Painful crisis episodes are poorly treated in sickle cell anemia, both in timeliness and appropriateness of care. Delayed treatment in Emergency Departments, unrelieved pain, frequent admissions, and prolonged hospitalizations are common. We establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fed60d26ae62efe954d9ad8371790b79
https://pubmed.ncbi.nlm.nih.gov/10666181
https://pubmed.ncbi.nlm.nih.gov/10666181
Autor:
A C, Rybicki, L J, Benjamin
Publikováno v:
Blood. 92(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c416701c5102aaea3b12d290da90fbd
https://pubmed.ncbi.nlm.nih.gov/9746804
https://pubmed.ncbi.nlm.nih.gov/9746804
Autor:
J J, Martin de Llano, W, Jones, K, Schneider, B T, Chait, J M, Manning, G, Rodgers, L J, Benjamin, B, Weksler
Publikováno v:
The Journal of biological chemistry. 268(36)
Previous studies had indicated that recombinant and natural human sickle hemoglobin had similar chemical properties (Martin de Llano, J. J., Schneewind, O., Stetler, G., and Manning, J. M. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 918-922). In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::497483b741601beb19bd846cec36d4e4
https://pubmed.ncbi.nlm.nih.gov/8262936
https://pubmed.ncbi.nlm.nih.gov/8262936
Publikováno v:
The Journal of laboratory and clinical medicine. 120(1)
Methyl acetyl phosphate specifically acetylates valine-1, lysine-82, and lysine-144 in the 2,3-diphosphoglycerate binding cleft of hemoglobin S, thereby inhibiting its gelation (greater than 32 gm/dl) at pH 7.4. To extend these findings, the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::058e3fc08d7fb2abf2daa1827c2c6cee
https://pubmed.ncbi.nlm.nih.gov/1613320
https://pubmed.ncbi.nlm.nih.gov/1613320
Autor:
L J, Benjamin, L R, Berkowitz, E, Orringer, V N, Mankad, A S, Prasad, L M, Lewkow, R K, Chillar, C M, Peterson
Publikováno v:
Blood. 67:1442-1447
We have recently completed a double-blind, placebo-controlled, noncrossover study, the goal of which was to determine whether cetiedil citrate (cetiedil) could affect the course of vaso-occlusive crises in sickle cell disease. Patients, who presented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b6471f0bec489498fd16dddf4a0442
https://doi.org/10.1182/blood.v67.5.1442.bloodjournal6751442
https://doi.org/10.1182/blood.v67.5.1442.bloodjournal6751442
Autor:
L J, Benjamin, J M, Manning
Publikováno v:
Blood. 67:544-546
Glyceraldehyde has been demonstrated to be an antisickling agent in vitro. In the present investigation, chromium-51 red cell studies were used to investigate the life span in vivo of sickle erythrocytes after treatment with glyceraldehyde in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad8dc29eb03449ba9701e84dfaf2a4f
https://doi.org/10.1182/blood.v67.2.544.bloodjournal672544
https://doi.org/10.1182/blood.v67.2.544.bloodjournal672544
Publikováno v:
Progress in clinical and biological research. 240
Methyl acetyl phosphate (MAP) is an acetylating agent which prevents the polymerization of sickle cell hemoglobin (HbS). MAP can penetrate sickle erythrocytes and can acetylate intracellular HbS. Tryptic peptide mapping of modified HbS on reversed ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ddb95c1509b87e0eb74fdc7cbdb562d
https://pubmed.ncbi.nlm.nih.gov/3615481
https://pubmed.ncbi.nlm.nih.gov/3615481